AIMC Topic: Amyotrophic Lateral Sclerosis
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Hypothalamic atrophy in primary lateral sclerosis, assessed by convolutional neural network-based automatic segmentation.
Scientific reports
Jan 10, 2025
Primary lateral sclerosis (PLS) is a motor neuron disease (MND) which mainly affects upper motor neurons. Within the MND spectrum, PLS is much more slowly progressive than amyotrophic laterals sclerosis (ALS). `Classical` ALS is characterized by cata...
Artificial intelligence empowered voice generation for amyotrophic lateral sclerosis patients.
Scientific reports
Jan 8, 2025
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that can result in a progressive loss of speech due to bulbar dysfunction, which can have significant negative impact on the patient's mental well-being. Alternative Augmentative Comm...
Selective diagnostics of Amyotrophic Lateral Sclerosis, Alzheimer's and Parkinson's Diseases with machine learning and miRNA.
Metabolic brain disease
Jan 2, 2025
The diagnosis of neurological diseases can be expensive, invasive, and inaccurate, as it is often difficult to distinguish between different types of diseases with similar motor symptoms. However, the dysregulation of miRNAs can be used to create a r...
Artificial Intelligence-Assisted Comparative Analysis of the Overlapping Molecular Pathophysiology of Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.
International journal of molecular sciences
Dec 15, 2024
The overlapping molecular pathophysiology of Alzheimer's Disease (AD), Amyotrophic Lateral Sclerosis (ALS), and Frontotemporal Dementia (FTD) was analyzed using relationships from a knowledge graph of 33+ million biomedical journal articles. The unsu...
Improving care for amyotrophic lateral sclerosis with artificial intelligence and affective computing.
Journal of the neurological sciences
Nov 25, 2024
BACKGROUND: Patients with ALS often face difficulties expressing emotions due to impairments in facial expression, speech, body language, and cognitive function. This study aimed to develop non-invasive AI tools to detect and quantify emotional respo...
An extensible and unifying approach to retrospective clinical data modeling: the BrainTeaser Ontology.
Journal of biomedical semantics
Aug 30, 2024
Automatic disease progression prediction models require large amounts of training data, which are seldom available, especially when it comes to rare diseases. A possible solution is to integrate data from different medical centres. Nevertheless, vari...
Intellectual assessment of amyotrophic lateral sclerosis using deep resemble forward neural network.
Neural networks : the official journal of the International Neural Network Society
Jun 19, 2024
ALS (Amyotrophic Lateral Sclerosis) is a neurodegenerative disorder causing profound physical disability that severely impairs a patient's life expectancy and quality of life. It also leads to muscular atrophy and progressive weakness of muscles due ...
What do you think caused your ALS? An analysis of the CDC national amyotrophic lateral sclerosis patient registry qualitative risk factor data using artificial intelligence and qualitative methodology.
Amyotrophic lateral sclerosis & frontotemporal degeneration
May 8, 2024
OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is an incurable, progressive neurodegenerative disease with a significant health burden and poorly understood etiology. This analysis assessed the narrative responses from 3,061 participants in the Cente...
Artificial intelligence for screening and diagnosis of amyotrophic lateral sclerosis: a systematic review and meta-analysis.
Amyotrophic lateral sclerosis & frontotemporal degeneration
Apr 2, 2024
INTRODUCTION: Amyotrophic lateral sclerosis (ALS) is a rare and fatal neurological disease that leads to progressive motor function degeneration. Diagnosing ALS is challenging due to the absence of a specific detection test. The use of artificial int...
AI-assisted automatic MRI-based tongue volume evaluation in motor neuron disease (MND).
International journal of computer assisted radiology and surgery
Mar 27, 2024
PURPOSE: Motor neuron disease (MND) causes damage to the upper and lower motor neurons including the motor cranial nerves, the latter resulting in bulbar involvement with atrophy of the tongue muscle. To measure tongue atrophy, an operator independen...
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