AIMC Topic: Animals
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Precision medicine in substance use disorders: Integrating behavioral, environmental, and biological insights.
Neuroscience and biobehavioral reviews
Aug 5, 2025
Substance use disorders (SUD) are chronic, relapsing conditions marked by high variability in treatment response and frequent relapse. This variability arises from complex interactions among behavioral, environmental, and biological factors unique to...
A computational framework for inferring species dynamics and interactions with applications in microbiota ecology.
NPJ systems biology and applications
Aug 5, 2025
We present MBPert, a generic computational framework for inferring species interactions and predicting dynamics in time-evolving ecosystems from perturbation and time-series data. In this work, we contextualize the framework in microbial ecosystem mo...
Bioinformatics analysis of Rho-signal transduction genes in postmenopausal osteoporosis and periodontitis.
Scientific reports
Aug 5, 2025
Postmenopausal osteoporosis (PMOP) increases the risk of periodontitis (PD), yet the shared mechanisms remain unclear. Rho-signal transduction genes may play a role due to their involvement in bone remodeling. This study aimed to explore Rho-related ...
Seeker-M: A bionic mantis shrimp robot with an adjustable-mass flexible spine.
Bioinspiration & biomimetics
Aug 5, 2025
To enhance the motion flexibility and environmental adaptability of underwater robots, this study proposes a novel design, Seeker-M, inspired by the locomotion mechanism of the mantis shrimp. The robot imitates the mantis shrimp's multi-pleopod swimm...
Recent progress in multifunctional theranostic hydrogels: the cornerstone of next-generation wound care technologies.
Biomaterials science
Aug 5, 2025
Theranostic hydrogels represent a groundbreaking approach by integrating therapeutic and diagnostic capabilities within a single platform, enabling real-time monitoring of wounds and precise treatment applications. These advanced materials are engine...
Subsecond Analysis of Locomotor Activity in Parkinsonian Mice.
eNeuro
Aug 5, 2025
The degeneration of midbrain dopamine (DA) neurons disrupts the neural control of natural behavior, such as walking, posture, and gait in Parkinson's disease. While some aspects of motor symptoms can be managed by DA replacement therapies, others res...
Integrative transcriptomic analysis reveals oligodendrocyte lineage switching in multiple sclerosis.
Life science alliance
Aug 4, 2025
Multiple sclerosis (MS) is a chronic disease of the central nervous system. The occurrence of MS is a phased process while its cause is still unclear. Here, by combining white matter single-nucleus transcriptomic datasets from MS and control samples,...
Prediction of the hypothalamus-pituitary organoid formation using machine learning.
Cell reports methods
Aug 4, 2025
Multi-cellular organoids are self-assembly aggregates that mimic biological functions and developmental processes of many tissue types in vitro. They are widely employed for disease modeling and functional studies. Hypothalamus-pituitary organoids ca...
Rapid, interpretable data-driven models of neural dynamics using recurrent mechanistic models.
Proceedings of the National Academy of Sciences of the United States of America
Aug 4, 2025
Obtaining predictive models of a neural system is notoriously challenging. Detailed models suffer from excess model complexity and are difficult to fit efficiently. Simplified models must negotiate a tradeoff between tractability, predictive power, a...
Prevalence, associated risk factors and satellite imagery analysis in predicting soil-transmitted helminth infection in Nakhon Si Thammarat Province, Thailand.
Scientific reports
Aug 4, 2025
Soil-transmitted helminth (STH) infections remain a significant public health concern in rural areas, often leading to nutritional and physical impairment, particularly in children. This study aimed to assess the prevalence and associated factors of ...
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