Hypertension is a leading cause of mortality worldwide, for which myriad treatment options are available. It is widely considered that continuous measurement of arterial blood pressure (BP) could improve the treatment of hypertension; however, chroni...
Monitoring mean arterial pressure (MAP) is essential for ensuring safe general anesthesia. Current practices rely either on non-invasive cuff measurements, which suffer from poor temporal resolution, or invasive arterial lines, which provide excellen...
BMC medical informatics and decision making
Sep 3, 2025
BACKGROUND AND OBJECTIVES: Brain tissue oxygenation is usually inferred from arterial partial pressure of oxygen (paO), which is in turn often inferred from pulse oximetry measurements or other non-invasive proxies. Our aim was to evaluate the feasib...
Journal of clinical monitoring and computing
Mar 25, 2025
Hypotension in perioperative and intensive care settings is a significant risk factor associated with complications such as myocardial infarction and kidney injury thereby increasing perioperative complications and mortality. Continuous blood pressur...
Every year, Coronary Artery Disease (CAD) claims lives of over a million people. CAD occurs when the coronary arteries, responsible for supplying oxygenated blood to the heart, get occluded due to plaque deposits on their inner walls. The most critic...
Journal of clinical monitoring and computing
Mar 6, 2025
The administration of propofol for sedation or general anesthesia presents challenges due to the complex relationship between patient factors and real-time physiological responses. This study explores the application of deep reinforcement learning (D...
Proceedings of the National Academy of Sciences of the United States of America
Feb 26, 2025
Analyzing cardiac pulse waveforms offers valuable insights into heart health and cardiovascular disease risk, although obtaining the more informative measurements from the central aorta remains challenging due to their invasive nature and limited non...
BACKGROUND: Intraoperative hypotension (IOH) and tachycardia are associated with perioperative myocardial injury (PMI), and thereby increased postoperative mortality. Patients undergoing vascular surgery are specifically at risk of developing cardiac...
BACKGROUND: Aortic coarctation (CoA) is a congenital anomaly leading to upper-body hypertension and lower-body hypotension. Despite surgical or interventional treatment, arterial hypertension may develop and contribute to morbidity and mortality. Con...
BACKGROUND: Due to their invasiveness, arterial lines are not typically used in routine monitoring, despite their superior responsiveness in hemodynamic monitoring and detecting intraoperative hypotension. To address this issue, noninvasive, continuo...
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