AIMC Topic: Brain

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Declaration of Computational Neurosurgery.

Advances in experimental medicine and biology
Computational neurosurgery is a novel and disruptive field where artificial intelligence and computational modeling are used to improve the diagnosis, treatment, and prognosis of patients affected by diseases of neurosurgical relevance. The field aim...

Computational Neurosurgery: Foundation.

Advances in experimental medicine and biology
Computational neurosurgery is a novel translational field where computational modeling and artificial intelligence are used to improve diagnosis, treatment, and prognosis of patients affected by diseases of neurosurgical relevance. By laying the foun...

DNeuroMAT: A Deep-Learning-Based Neuron Morphology Analysis Toolbox.

Methods in molecular biology (Clifton, N.J.)
Digital reconstruction of neuronal structures from 3D neuron microscopy images is critical for the quantitative investigation of brain circuits and functions. Currently, neuron reconstructions are mainly obtained by manual or semiautomatic methods. H...

Association between Resting Heart Rate and Machine Learning-Based Brain Age in Middle- and Older-Age.

The journal of prevention of Alzheimer's disease
BACKGROUND: Resting heart rate (RHR), has been related to increased risk of dementia, but the relationship between RHR and brain age is unclear.

Alzheimer's Disease Prediction Using Fly-Optimized Densely Connected Convolution Neural Networks Based on MRI Images.

The journal of prevention of Alzheimer's disease
Alzheimer's is a degenerative brain cell disease that affects around 5.8 million people globally. The progressive neurodegenerative disease known as Alzheimer's Disease (AD), affects the frontal cortex, the part of the brain in charge of memory, lang...

A Computational Framework for Memory Engrams.

Advances in neurobiology
Memory engrams in mice brains are potentially related to groups of concept cells in human brains. A single concept cell in human hippocampus responds, for example, not only to different images of the same object or person but also to its name written...

Screening Targets and Therapeutic Drugs for Alzheimer's Disease Based on Deep Learning Model and Molecular Docking.

Journal of Alzheimer's disease : JAD
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder caused by a complex interplay of various factors. However, a satisfactory cure for AD remains elusive. Pharmacological interventions based on drug targets are considered the most co...

Classifying Alzheimer's Disease Neuropathology Using Clinical and MRI Measurements.

Journal of Alzheimer's disease : JAD
BACKGROUND: Computer-aided machine learning models are being actively developed with clinically available biomarkers to diagnose Alzheimer's disease (AD) in living persons. Despite considerable work with cross-sectional in vivo data, many models lack...

Neural Sequences and the Encoding of Time.

Advances in experimental medicine and biology
Converging experimental and computational evidence indicate that on the scale of seconds the brain encodes time through changing patterns of neural activity. Experimentally, two general forms of neural dynamic regimes that can encode time have been o...

Updated Models of Alzheimer's Disease with Deep Neural Networks.

Journal of Alzheimer's disease : JAD
BACKGROUND: In recent years, researchers have focused on developing precise models for the progression of Alzheimer's disease (AD) using deep neural networks. Forecasting the progression of AD through the analysis of time series data represents a pro...