AIMC Topic: Bronchodilator Agents
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Energy Efficient Monitoring of Metered Dose Inhaler Usage.
Journal of medical systems
Oct 29, 2016
Life-long chronic inflammatory diseases of the airways, such as asthma and Chronic Obstructive Pulmonary Disease, are very common worldwide, affecting people of all ages, race and gender. One of the most important aspects for the effective management...
Pharmacokinetics of aclidinium bromide/formoterol fumarate fixed-dose combination compared with individual components: A phase 1, open-label, single-dose study.
Clinical pharmacology in drug development
Aug 24, 2015
Inhaled, long-acting bronchodilators represent a cornerstone of maintenance treatment for chronic obstructive pulmonary disease (COPD). Aclidinium bromide/formoterol fumarate 400/12 μg fixed-dose combination (FDC) has recently been licensed for use i...
Predictive machine learning algorithm for COPD exacerbations using a digital inhaler with integrated sensors.
BMJ open respiratory research
May 12, 2025
PURPOSE: By using data obtained with digital inhalers, machine learning models have the potential to detect early signs of deterioration and predict impending exacerbations of chronic obstructive pulmonary disease (COPD) for individual patients. This...
Discovering Pediatric Asthma Phenotypes on the Basis of Response to Controller Medication Using Machine Learning.
Annals of the American Thoracic Society
Jan 1, 2018
RATIONALE: Pediatric asthma has variable underlying inflammation and symptom control. Approaches to addressing this heterogeneity, such as clustering methods to find phenotypes and predict outcomes, have been investigated. However, clustering based o...
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