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Calcium Signaling

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A Model of a Synthetic Biological Communication Interface between Mammalian Cells and Mechatronic Systems.

IEEE transactions on nanobioscience
The creation of communication interfaces between abiotic and biotic systems represents a significant research challenge. In this work, we design and model a system linking the biochemical signaling pathways of mammalian cells to the actions of a mobi...

Detection of genetic cardiac diseases by Ca transient profiles using machine learning methods.

Scientific reports
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have revolutionized cardiovascular research. Abnormalities in Ca transients have been evident in many cardiac disease models. We have shown earlier that, by exploiting computation...