AIMC Topic: Carcinoma, Hepatocellular

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Prediction of treatment response and outcome of transarterial chemoembolization in patients with hepatocellular carcinoma using artificial intelligence: A systematic review of efficacy.

European journal of radiology
PURPOSE: To perform a systematic literature review of the efficacy of different AI models to predict HCC treatment response to transarterial chemoembolization (TACE), including overall survival (OS) and time to progression (TTP).

Multicategory matched learning for estimating optimal individualized treatment rules in observational studies with application to a hepatocellular carcinoma study.

Statistical methods in medical research
One primary goal of precision medicine is to estimate the individualized treatment rules that optimize patients' health outcomes based on individual characteristics. Health studies with multiple treatments are commonly seen in practice. However, most...

Contrast-enhanced ultrasound-based AI model for multi-classification of focal liver lesions.

Journal of hepatology
BACKGROUND & AIMS: Accurate multi-classification is a prerequisite for appropriate management of focal liver lesions (FLLs). Ultrasound is the most common imaging examination but lacks accuracy. Contrast-enhanced ultrasound (CEUS) offers better perfo...

Cellular Senescence in Hepatocellular Carcinoma: Immune Microenvironment Insights via Machine Learning and In Vitro Experiments.

International journal of molecular sciences
Hepatocellular carcinoma (HCC), a leading liver tumor globally, is influenced by diverse risk factors. Cellular senescence, marked by permanent cell cycle arrest, plays a crucial role in cancer biology, but its markers and roles in the HCC immune mic...

Extraction and classification of structured data from unstructured hepatobiliary pathology reports using large language models: a feasibility study compared with rules-based natural language processing.

Journal of clinical pathology
AIMS: Structured reporting in pathology is not universally adopted and extracting elements essential to research often requires expensive and time-intensive manual curation. The accuracy and feasibility of using large language models (LLMs) to extrac...

Opioid growth factor receptor overexpression exerts anti-hepatocellular carcinoma effects by activating P16 and P21 to inhibit proliferation and migration of HepG2 cells.

Folia histochemica et cytobiologica
INTRODUCTION: Hepatocellular carcinoma (HCC) is the sixth most common type of cancer and the second leading cause of cancer death worldwide [19]. Opioid growth factor (OGF) has been shown to exhibit antitumour potential, binding to OGF receptor (OGFr...

Characterization of hepatocellular carcinoma with CT with deep learning reconstruction compared with iterative reconstruction and 3-Tesla MRI.

European radiology
OBJECTIVES: This study compared the characteristics of lesions suspicious for hepatocellular carcinoma (HCC) and their LI-RADS classifications in adaptive statistical iterative reconstruction (ASIR) and deep learning reconstruction (DLR) to those of ...

Integrating single cell analysis and machine learning methods reveals stem cell-related gene S100A10 as an important target for prediction of liver cancer diagnosis and immunotherapy.

Frontiers in immunology
BACKGROUND: Hepatocellular carcinoma (LIHC) poses a significant health challenge worldwide, primarily due to late-stage diagnosis and the limited effectiveness of current therapies. Cancer stem cells are known to play a role in tumor development, met...

Automated ultrasonography of hepatocellular carcinoma using discrete wavelet transform based deep-learning neural network.

Medical image analysis
This study introduces HCC-Net, a novel wavelet-based approach for the accurate diagnosis of hepatocellular carcinoma (HCC) from abdominal ultrasound (US) images using artificial neural networks. The HCC-Net integrates the discrete wavelet transform (...