AIMC Topic: Child Development

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Scientific and Regulatory Considerations for an Ontogeny Knowledge Base for Pediatric Clinical Pharmacology.

Clinical pharmacology and therapeutics
Understanding all aspects of developmental biology, or pediatric ontogeny, that affect drug therapy from the fetus to the adolescent child is the holy grail of pediatric scientists and clinical pharmacologists. The scientific community is now close t...

Bone age assessment with various machine learning techniques: A systematic literature review and meta-analysis.

PloS one
BACKGROUND: The assessment of bone age and skeletal maturity and its comparison to chronological age is an important task in the medical environment for the diagnosis of pediatric endocrinology, orthodontics and orthopedic disorders, and legal enviro...

Longitudinal Prediction of Infant Diffusion MRI Data via Graph Convolutional Adversarial Networks.

IEEE transactions on medical imaging
Missing data is a common problem in longitudinal studies due to subject dropouts and failed scans. We present a graph-based convolutional neural network to predict missing diffusion MRI data. In particular, we consider the relationships between sampl...

Regression Convolutional Neural Network for Automated Pediatric Bone Age Assessment From Hand Radiograph.

IEEE journal of biomedical and health informatics
Skeletal bone age assessment is a common clinical practice to investigate endocrinology, and genetic and growth disorders of children. However, clinical interpretation and bone age analyses are time-consuming, labor intensive, and often subject to in...

Robot-based intervention may reduce delay in the production of intransitive gestures in Chinese-speaking preschoolers with autism spectrum disorder.

Molecular autism
BACKGROUND: Past studies have shown that robot-based intervention was effective in improving gestural use in children with autism spectrum disorders (ASD). The present study examined whether children with ASD could catch up to the level of gestural p...

Multi-task prediction of infant cognitive scores from longitudinal incomplete neuroimaging data.

NeuroImage
Early postnatal brain undergoes a stunning period of development. Over the past few years, research on dynamic infant brain development has received increased attention, exhibiting how important the early stages of a child's life are in terms of brai...

Creepiness Creeps In: Uncanny Valley Feelings Are Acquired in Childhood.

Child development
The uncanny valley posits that very human-like robots are unsettling, a phenomenon amply demonstrated in adults but unexplored in children. Two hundred forty 3- to 18-year-olds viewed one of two robots (machine-like or very human-like) and rated thei...

Detecting Abnormal Word Utterances in Children With Autism Spectrum Disorders: Machine-Learning-Based Voice Analysis Versus Speech Therapists.

Perceptual and motor skills
Abnormal prosody is often evident in the voice intonations of individuals with autism spectrum disorders. We compared a machine-learning-based voice analysis with human hearing judgments made by 10 speech therapists for classifying children with auti...

Association between abnormal brain functional connectivity in children and psychopathology: A study based on graph theory and machine learning.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
OBJECTIVES: One of the major challenges facing psychiatry is how to incorporate biological measures in the classification of mental health disorders. Many of these disorders affect brain development and its connectivity. In this study, we propose a n...

A comparison of the efficacy of weight-shift vs. joystick control of a robotic mobility device by infants ages 5 to 10 months.

Assistive technology : the official journal of RESNA
The onset of crawling in infants contributes to cognitive, perceptual, social, and emotional development. Conversely, infants with motor impairment that delays or prevents autonomous mobility often have associated developmental delays. Evidence sugge...