AIMC Topic: Clinical Relevance

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Hub biomarkers and their clinical relevance in glycometabolic disorders: A comprehensive bioinformatics and machine learning approach.

Chinese medical journal
BACKGROUND: Gluconeogenesis is a critical metabolic pathway for maintaining glucose homeostasis, and its dysregulation can lead to glycometabolic disorders. This study aimed to identify hub biomarkers of these disorders to provide a theoretical found...

Clinical relevance of computationally derived tubular features and their spatial relationships with the interstitial microenvironment in minimal change disease/focal segmental glomerulosclerosis.

Kidney international
BACKGROUND: Visual scoring of tubular damage has limitations in capturing the full spectrum of structural changes and prognostic potential. Here, we investigated if computationally quantified tubular features can enhance prognostication and reveal sp...

Comparative analysis of clinical relevance and accuracy in AI-assisted patient consultations on ankle and clavicle fracture surgeries.

Injury
BACKGROUND: It is becoming increasingly important to evaluate the effectiveness of large language models (LLMs) and query-assisted platforms like Google and ChatGPT in providing clinically relevant and accurate information to patient-initiated inquir...

[Preoperative anal function assessment in sphincter-preserving surgery for rectal cancer: clinical significance and strategies].

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
Sphincter-preserving surgery has become the mainstream approach for mid-to-low rectal cancer, yet postoperative anal dysfunction (low anterior resection syndrome, LARS) occurs in 30%-50% of patients, significantly impacting quality of life. This revi...

Clinical Importance of 3D Volography in Breast Imaging.

Advances in experimental medicine and biology
The clinical applications of the volography algorithm and concomitant refraction-corrected reflection algorithm as described in Chap. 10 are discussed here. Comparisons with an H&E stained image, discussion of glandular tissue visibility, related bio...