Studies in health technology and informatics
May 25, 2022
In health sciences, high-quality text embeddings may augment qualitative data analysis of large amounts of text by enabling, e.g., searching and clustering of health information. This study aimed to evaluate three different sentence-level embedding m...
As complex systems, dynamic networks have obvious nonlinear features. Detecting communities in dynamic networks is of great importance for understanding the functions of networks and mining evolving relationships. Recently, some network embedding-bas...
Single-cell RNA sequencing (scRNA-seq) permits researchers to study the complex mechanisms of cell heterogeneity and diversity. Unsupervised clustering is of central importance for the analysis of the scRNA-seq data, as it can be used to identify put...
Dimensionality reduction is a data transformation technique widely used in various fields of genomics research. The application of dimensionality reduction to genotype data is known to capture genetic similarity between individuals, and is used for v...
AIMS: Dynamic retinal vessel analysis (DVA) provides a non-invasive way to assess microvascular function in patients and potentially to improve predictions of individual cardiovascular (CV) risk. The aim of our study was to use untargeted machine lea...
High-throughput single-cell RNA-seq data have provided unprecedented opportunities for deciphering the regulatory interactions among genes. However, such interactions are complex and often nonlinear or nonmonotonic, which makes their inference using ...
Since its selection as the method of the year in 2013, single-cell technologies have become mature enough to provide answers to complex research questions. With the growth of single-cell profiling technologies, there has also been a significant incre...
The emergence of single cell RNA sequencing has facilitated the studied of genomes, transcriptomes and proteomes. As available single-cell RNA-seq datasets are released continuously, one of the major challenges facing traditional RNA analysis tools i...
Studies in health technology and informatics
Jan 14, 2022
Population Health Management typically relies on subjective decisions to segment and stratify populations. This study combines unsupervised clustering for segmentation and supervised classification, personalised to clusters, for stratification. An in...
Mathematical biosciences and engineering : MBE
Jan 7, 2022
It is vital for the annotation of uncharacterized proteins by protein function prediction. At present, Deep Neural Network based protein function prediction is mainly carried out for dataset of small scale proteins or Gene Ontology, and usually explo...
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