The immune system is of critical importance in the development of cancer. The evasion of destruction by the immune system is one of the emerging hallmarks of cancer. We have built a dataset of 171,166 manually annotated CD3 and CD8 cells, which we us...
International journal of computer assisted radiology and surgery
May 25, 2019
PURPOSE: The gold standard for colorectal cancer metastases detection in the peritoneum is histological evaluation of a removed tissue sample. For feedback during interventions, real-time in vivo imaging with confocal laser microscopy has been propos...
BACKGROUND: Gene shaving (GS) is an essential and challenging tools for biomedical researchers due to the large number of genes in human genome and the complex nature of biological networks. Most GS methods are not applicable to non-linear and multi-...
Computer methods and programs in biomedicine
Apr 10, 2019
OBJECTIVE: A colon microarray data is a repository of thousands of gene expressions with different strengths for each cancer cell. It is necessary to detect which genes are responsible for cancer growth. This study presents an exhaustive comparative ...
The colon cancer is formed by uncontrollable growth of abnormal cells in large intestine or colon that can affect both men and women and it is third cancer disease in the world. At present, Wireless Capsule Endoscopy (WCE) screening method is utilize...
Biometrical journal. Biometrische Zeitschrift
Dec 12, 2018
An issue for class-imbalanced learning is what assessment metric should be employed. So far, precision-recall curve (PRC) as a metric is rarely used in practice as compared with its alternative of receiver operating characteristic (ROC). This study i...
The detection and removal of precancerous polyps via colonoscopy is the gold standard for the prevention of colon cancer. However, the detection rate of adenomatous polyps can vary significantly among endoscopists. Here, we show that a machine-learni...
Journal of clinical monitoring and computing
Sep 24, 2018
Standardized clinical pathways are useful tool to reduce variation in clinical management and may improve quality of care. However the evidence supporting a specific clinical pathway for a patient or patient population is often imperfect limiting ado...
Journal of laparoendoscopic & advanced surgical techniques. Part A
Jun 7, 2018
Laparoscopic complete mesocolic excision (CME) for transverse colon cancer is technically challenging. Robotic technology has been developed to reduce technical limitations of laparoscopy. Yet, no data are available on the role of robotic approach f...
BACKGROUND: ADR is a widely used colonoscopy quality indicator. Calculation of ADR is labor-intensive and cumbersome using current electronic medical databases. Natural language processing (NLP) is a method used to extract meaning from unstructured o...
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