AIMC Topic: Computational Biology

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Improved prediction of smoking status via isoform-aware RNA-seq deep learning models.

PLoS computational biology
Most predictive models based on gene expression data do not leverage information related to gene splicing, despite the fact that splicing is a fundamental feature of eukaryotic gene expression. Cigarette smoking is an important environmental risk fac...

iMPT-FDNPL: Identification of Membrane Protein Types with Functional Domains and a Natural Language Processing Approach.

Computational and mathematical methods in medicine
Membrane protein is an important kind of proteins. It plays essential roles in several cellular processes. Based on the intramolecular arrangements and positions in a cell, membrane proteins can be divided into several types. It is reported that the ...

Application of Medical Imaging Based on Deep Learning in the Treatment of Lumbar Degenerative Diseases and Osteoporosis with Bone Cement Screws.

Computational and mathematical methods in medicine
OBJECTIVE: To explore the application value of magnetic resonance spectroscopy (MRS) and GSI-energy spectrum electronic computed tomography (CT) medical imaging based on the deep convolutional neural network (CNN) in the treatment of lumbar degenerat...

Emotion Recognition Based on EEG Using Generative Adversarial Nets and Convolutional Neural Network.

Computational and mathematical methods in medicine
Emotion recognition plays an important role in the field of human-computer interaction (HCI). Automatic emotion recognition based on EEG is an important topic in brain-computer interface (BCI) applications. Currently, deep learning has been widely us...

AoP-LSE: Antioxidant Proteins Classification Using Deep Latent Space Encoding of Sequence Features.

Current issues in molecular biology
It is of utmost importance to develop a computational method for accurate prediction of antioxidants, as they play a vital role in the prevention of several diseases caused by oxidative stress. In this correspondence, we present an effective computat...

Prediction for understanding the effectiveness of antiviral peptides.

Computational biology and chemistry
The low efficacy of current antivirals in conjunction with the resistance of viruses against existing antiviral drugs has resulted in the demand for the development of novel antiviral agents. Antiviral peptides (AVPs) are those bioactive peptides hav...

Simulation and Prediction of Fungal Community Evolution Based on RBF Neural Network.

Computational and mathematical methods in medicine
Simulation and prediction of the scale change of fungal community. First, using the experimental data of a variety of fungal decomposition activities, a mathematical model of the decomposition rate and the relationship between the bacterial species w...

A Liver Segmentation Method Based on the Fusion of VNet and WGAN.

Computational and mathematical methods in medicine
Accurate segmentation of liver images is an essential step in liver disease diagnosis, treatment planning, and prognosis. In recent years, although liver segmentation methods based on 2D convolutional neural networks have achieved good results, there...

SMBFT: A Modified Fuzzy -Means Algorithm for Superpixel Generation.

Computational and mathematical methods in medicine
Most traditional superpixel segmentation methods used binary logic to generate superpixels for natural images. When these methods are used for images with significantly fuzzy characteristics, the boundary pixels sometimes cannot be correctly classifi...

Protein Family Classification from Scratch: A CNN Based Deep Learning Approach.

IEEE/ACM transactions on computational biology and bioinformatics
Next-generation sequencing techniques provide us with an opportunity for generating sequenced proteins and identifying the biological families and functions of these proteins. However, compared with identified proteins, uncharacterized proteins consi...