Electrocardiogram (ECG) signal is critical to the classification of cardiac arrhythmia using some machine learning methods. In practice, the ECG datasets are usually with multiple missing values due to faults or distortion. Unfortunately, many establ...
Despite the success and fast adaptation of deep learning models in biomedical domains, their lack of interpretability remains an issue. Here, we introduce Enhanced Integrated Gradients (EIG), a method to identify significant features associated with ...
Rice microRNAs (miRNAs) are important post-transcriptional regulation factors and play vital roles in many biological processes, such as growth, development, and stress resistance. Identification of these molecules is the basis of dissecting their re...
Journal of computer-aided molecular design
Jun 16, 2020
Phage virion protein (PVP) perforate the host cell membrane and eventually culminates in cell rupture thereby releasing replicated phages. The accurate identification of PVP is thus a crucial step towards improving our understanding of the biological...
Human strongyloidiasis is a serious disease mostly attributable to Strongyloides stercoralis and to a lesser extent Strongyloides fuelleborni, a parasite mainly of non-human primates. The role of animals as reservoirs of human-infecting Strongyloides...
OBJECTIVE: Familial adenomatous polyposis (FAP) is one major type of inherited duodenal cancer. The estimate of duodenal cancer risk in patients with FAP is critical for selecting the optimal treatment strategy.
Protein-protein interactions (PPIs) are important for almost all cellular processes, including metabolic cycles, DNA transcription and replication, and signaling cascades. The experimental methods for identifying PPIs are always time-consuming and ex...
Interdisciplinary sciences, computational life sciences
Jun 12, 2020
In the tremendous field of the bioinformatics look into, enormous volume of genetic information has been produced. Higher throughput gadgets are made accessible at lower cost made the age of Big data. In a time of developing information multifaceted ...
Computational and mathematical methods in medicine
Jun 11, 2020
This paper proposes a deep learning method based on electrical impedance tomography (EIT) to estimate the thickness of abdominal subcutaneous fat. EIT for evaluating the thickness of abdominal subcutaneous fat is an absolute imaging problem that aims...
MOTIVATION: Alternative splicing makes significant contributions to functional diversity of transcripts and proteins. Many alternatively spliced gene isoforms have been shown to perform specific biological functions under different contexts. In addit...
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