AIMC Topic: Computational Biology

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Natural Language Processing for EHR-Based Computational Phenotyping.

IEEE/ACM transactions on computational biology and bioinformatics
This article reviews recent advances in applying natural language processing (NLP) to Electronic Health Records (EHRs) for computational phenotyping. NLP-based computational phenotyping has numerous applications including diagnosis categorization, no...

Detecting Succinylation sites from protein sequences using ensemble support vector machine.

BMC bioinformatics
BACKGROUND: Lysine succinylation is a new kind of post-translational modification which plays a key role in protein conformation regulation and cellular function control. To understand the mechanism of succinylation profoundly, it is necessary to ide...

A Data Driven Model for Predicting RNA-Protein Interactions based on Gradient Boosting Machine.

Scientific reports
RNA protein interactions (RPI) play a pivotal role in the regulation of various biological processes. Experimental validation of RPI has been time-consuming, paving the way for computational prediction methods. The major limiting factor of these meth...

Multi-Factored Gene-Gene Proximity Measures Exploiting Biological Knowledge Extracted from Gene Ontology: Application in Gene Clustering.

IEEE/ACM transactions on computational biology and bioinformatics
To describe the cellular functions of proteins and genes, a potential dynamic vocabulary is Gene Ontology (GO), which comprises of three sub-ontologies namely, Biological-process, Cellular-component, and Molecular-function. It has several application...

The effect of structure on image classification using signatures.

Biological cybernetics
Humans recognize transformed images from a very small number of samples. Inspired by this idea, we evaluate a classification method that requires only one sample per class, while providing invariance to image transformations generated by a compact gr...

Deep Learning for Plant Species Classification Using Leaf Vein Morphometric.

IEEE/ACM transactions on computational biology and bioinformatics
An automated plant species identification system could help botanists and layman in identifying plant species rapidly. Deep learning is robust for feature extraction as it is superior in providing deeper information of images. In this research, a new...

Rough sets and Laplacian score based cost-sensitive feature selection.

PloS one
Cost-sensitive feature selection learning is an important preprocessing step in machine learning and data mining. Recently, most existing cost-sensitive feature selection algorithms are heuristic algorithms, which evaluate the importance of each feat...

From lexical regularities to axiomatic patterns for the quality assurance of biomedical terminologies and ontologies.

Journal of biomedical informatics
Ontologies and terminologies have been identified as key resources for the achievement of semantic interoperability in biomedical domains. The development of ontologies is performed as a joint work by domain experts and knowledge engineers. The maint...

Sum Rate of MISO Neuro-Spike Communication Channel With Constant Spiking Threshold.

IEEE transactions on nanobioscience
Communication among neurons, known as neuro-spike communication, is the most promising technique for realization of a bio-inspired nanoscale communication paradigm to achieve biocompatible nanonetworks. In neuro-spike communication, the information, ...