AIMC Topic: Computer-Aided Design

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On extracting design principles from biology: I. Method-General answers to high-level design questions for bioinspired robots.

Bioinspiration & biomimetics
When millions of years of evolution suggest a particular design solution, we may be tempted to abandon traditional design methods and copy the biological example. However, biological solutions do not often translate directly into the engineering doma...

Confined swimming of bio-inspired microrobots in rectangular channels.

Bioinspiration & biomimetics
Controlled swimming of bio-inspired microrobots in confined spaces needs to be understood well for potential use in medical applications in conduits and vessels inside the body. In this study, experimental and computational studies are performed for ...

A bioinspired multi-modal flying and walking robot.

Bioinspiration & biomimetics
With the aim to extend the versatility and adaptability of robots in complex environments, a novel multi-modal flying and walking robot is presented. The robot consists of a flying wing with adaptive morphology that can perform both long distance fli...

A comparative study of family-specific protein-ligand complex affinity prediction based on random forest approach.

Journal of computer-aided molecular design
The assessment of binding affinity between ligands and the target proteins plays an essential role in drug discovery and design process. As an alternative to widely used scoring approaches, machine learning methods have also been proposed for fast pr...

Active-learning strategies in computer-assisted drug discovery.

Drug discovery today
High-throughput compound screening is time and resource consuming, and considerable effort is invested into screening compound libraries, profiling, and selecting the most promising candidates for further testing. Active-learning methods assist the s...

Design and control of the MINDWALKER exoskeleton.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Powered exoskeletons can empower paraplegics to stand and walk. Actively controlled hip ab/adduction (HAA) is needed for weight shift and for lateral foot placement to support dynamic balance control and to counteract disturbances in the frontal plan...

A novel robotic platform for laser-assisted transurethral surgery of the prostate.

IEEE transactions on bio-medical engineering
Benign prostatic hyperplasia (BPH) is the most common pathology afflicting ageing men. The gold standard for the surgical treatment of BPH is transurethral resection of the prostate. The laser-assisted transurethral surgical treatment of BPH is recen...

Integrative strategies in drug discovery: Harnessing genomics, deep learning, and computer-aided drug design.

Computational biology and chemistry
The development of novel drugs increasingly relies on advanced omics technologies, including genomics, transcriptomics, proteomics, and metabolomics. These approaches provide insights into genetic mutations, biomarkers, and disease pathways. However,...

User experience of and satisfaction with computer-aided design software when designing dental prostheses: a multicenter survey study.

International journal of computerized dentistry
AIM: The present study aimed to compare the responses and satisfaction reported by users with varying levels of experience regarding different types of CAD software programs to design crowns.

The Role of Digital Technologies in Personalized Craniomaxillofacial Surgical Procedures.

Oral and maxillofacial surgery clinics of North America
Craniomaxillofacial (CMF) surgery addresses complex challenges, balancing aesthetic and functional restoration. Digital technologies, including advanced imaging, virtual surgical planning, computer-aided design, and 3D printing, have revolutionized t...