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Computer-Aided Design

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[Animal experiment on the accuracy of the Autonomous Dental Implant Robotic System].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
To evaluate the accuracy of the Autonomous Dental Implant Robotic System (ADIR) through animal experiments. Nine canine models with bilateral mandibular premolars loss were prepared. Two implants were placed in each side of canine's mandibular ede...

[Trend of collaboration and sharing in digitalized restorative dentistry].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
To digitalize restorative dentistry means to digitalize all the approaches involved in the clinical diagnosis and treatment process, in the production of individualized restorations, in the information transmission and communication between dentists ...

Three-dimensional direct laser writing of biomimetic neuron structures.

Optics express
Building biomimetic neuron structures that emulate the topological features of biological neural networks at multiple scales has been an active area in neuron cell culturing, neuron-chip interface and computer chip design. However, due to the fact th...

Development of a snake-like dexterous manipulator for skull base surgery.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Petrous apex lesions constitute considerable surgical challenges due to their location in the skull base and close relationship with critical structures such as inner ear, carotid arteries, facial nerves and jugular bulb. These lesions often cannot b...

Using Deep Learning for Compound Selectivity Prediction.

Current computer-aided drug design
Compound selectivity prediction plays an important role in identifying potential compounds that bind to the target of interest with high affinity. However, there is still short of efficient and accurate computational approaches to analyze and predict...

Artificial Neural Network Analysis of Pharmacokinetic and Toxicity Properties of Lead Molecules for Dengue Fever, Tuberculosis and Malaria.

Current computer-aided drug design
Poor pharmacokinetic and toxicity profiles are major reasons for the low rate of advancing lead drug candidates into efficacy studies. The In-silico prediction of primary pharmacokinetic and toxicity properties in the drug discovery and development p...

Participatory design and validation of mobility enhancement robotic wheelchair.

Journal of rehabilitation research and development
The design of the mobility enhancement robotic wheelchair (MEBot) was based on input from electric powered wheelchair (EPW) users regarding the conditions they encounter when driving in both indoor and outdoor environments that may affect their safet...

Design of a biped robot actuated by pneumatic artificial muscles.

Bio-medical materials and engineering
High compliant legs are essential for the efficient versatile locomotion and shock absorbency of humans. This study proposes a biped robot actuated by pneumatic artificial muscles to mimic human locomotion. On the basis of the musculoskeletal archite...

Experiments and kinematics analysis of a hand rehabilitation exoskeleton with circuitous joints.

Bio-medical materials and engineering
Aiming at the hand rehabilitation of stroke patients, a wearable hand exoskeleton with circuitous joint is proposed. The circuitous joint adopts the symmetric pinion and rack mechanism (SPRM) with the parallel mechanism. The exoskeleton finger is a s...

Design of a quasi-passive 3 DOFs ankle-foot wearable rehabilitation orthosis.

Bio-medical materials and engineering
Muscular rigidity and atrophy caused by long-term underactivity usually lead to foot drop, strephenopodia, foot extorsion or some other complications for the lower limb movement disorders or lower limb surgery sufferers. The ankle-foot orthosis can h...