AIMC Topic: Computer-Aided Design

Clear Filters Showing 161 to 170 of 180 articles

In silico design strategies for tubulin inhibitors for the development of anticancer therapies.

Expert opinion on drug discovery
INTRODUCTION: Microtubules, composing of α, β-tubulin dimers, are important for cellular processes like proliferation and transport, thereby they become suitable targets for research in cancer. Existing candidates often exhibit off-target effects, ne...

Morphological effects of input data quantity in AI-powered dental crown design.

Journal of dentistry
OBJECTIVES: This retrospective in vitro study evaluated the impact of input data quantity on the morphology of dental crowns generated by AI-based software. The hypothesis suggests that increased input data quantity improves the quality of generated ...

Computer-Aided Drug Discovery for Undruggable Targets.

Chemical reviews
Undruggable targets are those of therapeutical significance but challenging for conventional drug design approaches. Such targets often exhibit unique features, including highly dynamic structures, a lack of well-defined ligand-binding pockets, the p...

Don't Fear AI Replacing You as a Dentist-Yet.

Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)
The dental profession has evolved rapidly in recent years-from digital imaging and CAD/CAM restorations to the integration of artificial intelligence (AI) in diagnostics and treatment planning. Understandably, many dentists wonder whether AI could so...

[Machine learning-aided design of synthetic biological parts and circuits].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Synthetic biology is an emerging interdisciplinary field at the convergence of biology, engineering, and computer science. It employs a bottom-up approach to progressively design biological parts, devices, and circuits, aiming to create artificial bi...

Complete Digital Workflow for Fabricating an Occlusal Device Using Artificial Intelligence- Powered Design Software and Additive Manufacturing: A Dental Method.

The International journal of prosthodontics
Artificial intelligence (AI) has been expanding into areas that were thought to be reserved for human experts and has a tremendous potential to improve patient care and revolutionize the healthcare field. Recently launched AI-powered dental design so...

Recent Trends in Computer-aided Drug Design for Anti-cancer Drug Discovery.

Current topics in medicinal chemistry
Cancer is considered one of the deadliest diseases globally, and continuous research is being carried out to find novel potential therapies for myriad cancer types that affect the human body. Researchers are hunting for innovative remedies to minimiz...

[Independent innovation research, development and transformation of precise bionic repair technology for oral prosthesis].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
According to the fourth national oral health epidemiological survey report (2018), billions of teeth are lost or missing in China, inducing chewing dysfunction, which is necessary to build physiological function using restorations. Digital technology...

DeepLearnMOR: a deep-learning framework for fluorescence image-based classification of organelle morphology.

Plant physiology
The proper biogenesis, morphogenesis, and dynamics of subcellular organelles are essential to their metabolic functions. Conventional techniques for identifying, classifying, and quantifying abnormalities in organelle morphology are largely manual an...

[Animal experiment on the accuracy of the Autonomous Dental Implant Robotic System].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
To evaluate the accuracy of the Autonomous Dental Implant Robotic System (ADIR) through animal experiments. Nine canine models with bilateral mandibular premolars loss were prepared. Two implants were placed in each side of canine's mandibular ede...