AIMC Topic: Computer Simulation

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Reference-free calibration method for asynchronous rotation in robotic CT.

Journal of X-ray science and technology
BACKGROUND: Geometry calibration for robotic CT system is necessary for obtaining acceptable images under the asynchrony of two manipulators.

Design and Stability Analysis of an Adaptive Neuro-Fuzzy Inference System (ANFIS)-Based Pacemaker Controller in MATLAB Simulink.

Journal of long-term effects of medical implants
We present the design and stability analysis of an adaptive neuro-fuzzy inference system (ANFIS)-based controller of a pacemaker in MATLAB Simulink. ANFIS uses learning and speed properties of fuzzy and neural networks. Based on body states and prepr...

In-silico prediction of anti-breast cancer activity of ginger (Zingiber officinale) using machine learning techniques.

Breast disease
INTRODUCTION: Indonesian civilization extensively uses traditional medicine to cure illnesses and preserve health. The lack of knowledge on the security and efficacy of medicinal plants is still a significant concern. Although the precise chemicals r...

Peptidic Compound as DNA Binding Agent: Fragment-based Design, Machine Learning, Molecular Modeling, Synthesis, and DNA Binding Evaluation.

Protein and peptide letters
BACKGROUND: Cancer remains a global burden, with increasing mortality rates. Current cancer treatments involve controlling the transcription of malignant DNA genes, either directly or indirectly. DNA exhibits various structural forms, including the G...

In Silico Clinical Trials: Is It Possible?

Methods in molecular biology (Clifton, N.J.)
Modeling and simulation (M&S), including in silico (clinical) trials, helps accelerate drug research and development and reduce costs and have coined the term "model-informed drug development (MIDD)." Data-driven, inferential approaches are now becom...

Three-dimensional force detection and decoupling of a fiber grating sensor for a humanoid prosthetic hand.

Optics express
A fiber Bragg grating (FBG) based three-dimensional (3D) force sensor for a humanoid prosthetic hand is designed, which can precisely detect 3D force and compensate for ambient temperature. FBG was encapsulated in polydimethylsiloxane (PDMS) for forc...

Inference of Coalescence Times and Variant Ages Using Convolutional Neural Networks.

Molecular biology and evolution
Accurate inference of the time to the most recent common ancestor (TMRCA) between pairs of individuals and of the age of genomic variants is key in several population genetic analyses. We developed a likelihood-free approach, called CoalNN, which use...

Efficient prediction of peptide self-assembly through sequential and graphical encoding.

Briefings in bioinformatics
In recent years, there has been an explosion of research on the application of deep learning to the prediction of various peptide properties, due to the significant development and market potential of peptides. Molecular dynamics has enabled the effi...

Creation and Adoption of Large Language Models in Medicine.

JAMA
IMPORTANCE: There is increased interest in and potential benefits from using large language models (LLMs) in medicine. However, by simply wondering how the LLMs and the applications powered by them will reshape medicine instead of getting actively in...