AIMC Topic: Cyclic AMP Response Element-Binding Protein

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Achyranthes Bidentata Radix mitigates neuronal apoptosis via regulation of JUN and CREB in the cAMP signaling pathway.

Phytomedicine : international journal of phytotherapy and phytopharmacology Jul 5, 2025
BACKGROUND: Although Achyranthes Bidentata Radix (ABR) demonstrates neuroprotective potential in NDDs, its anti-apoptotic mechanisms remain unclear.
Cyclic AMP Response Element-Binding Protein Neuroprotective Agents Neurons Cell Line Mice Plant Roots Apoptosis Signal Transduction Achyranthes Cyclic AMP Animals Proto-Oncogene Proteins c-jun Zebrafish
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Effects of exogenous energy on synthesis of steroid hormones and expression characteristics of the CREB/StAR signaling pathway in theca cells of laying hen.

Poultry science Dec 30, 2023
Energy and the cAMP-response element binding protein (CREB)/steroidogenic acute regulatory protein (StAR) signaling pathway play important roles in steroid hormone production and follicular development in hens. This present study aimed to investigate...
Theca Cells Cyclic AMP Response Element-Binding Protein Glucose Steroidogenic Acute Regulatory Protein Phosphoproteins Granulosa Cells Progesterone Signal Transduction Chickens Animals Steroids Female
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Common cancer biomarkers of breast and ovarian types identified through artificial intelligence.

Chemical biology & drug design May 15, 2020
Biomarkers can offer great promise for improving prevention and treatment of complex diseases such as cancer, cardiovascular diseases, and diabetes. These can be used as either diagnostic or predictive or as prognostic biomarkers. The revolution brou...
Breast Neoplasms Biomarkers, Tumor Female Cyclic AMP Response Element-Binding Protein Activating Transcription Factor 2 Ovarian Neoplasms Cluster Analysis Artificial Intelligence Humans
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Identification of esophageal cancer pathway deviation and construction of a diagnosis model using three kernel genes.

Journal of cellular physiology Mar 5, 2019
The purpose of this study is to better understand the role of interleukin 35 (IL35) in esophageal carcinoma by comparing the mRNA level in Barrett's esophageal mucosa and in matched normal squamous mucosa and to understand how the diagnosis model wor...
Interleukin-12 Subunit p35 Esophageal Squamous Cell Carcinoma Hepatocyte Nuclear Factor 1-beta Cyclic AMP Response Element-Binding Protein Transcriptome Deep Learning Case-Control Studies Biomarkers, Tumor Gene Expression Profiling Reproducibility of Results Nerve Tissue Proteins Early Detection of Cancer Esophageal Neoplasms Predictive Value of Tests Models, Genetic Databases, Genetic Gene Expression Regulation, Neoplastic Humans
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