To address the imbalanced classification problem emerging in Bioinformatics, a boundary movement-based extreme learning machine (ELM) algorithm called BM-ELM was proposed. BM-ELM tries to firstly explore the prior information about data distribution ...
G-protein-coupled receptors (GPCRs) are seven membrane-spanning proteins and regulate many important physiological processes, such as vision, neurotransmission, immune response and so on. GPCRs-related pathways are the targets of a large number of ma...
In this paper, we introduce a new powerful scientific paradigm to understand natural and cultural processes. This new paradigm is based on two fundamental keywords: Data, as representative sample of the process we need to analyze, and Artificial Adap...
IEEE/ACM transactions on computational biology and bioinformatics
Jan 1, 2015
A major challenge in computational biology is to find simple representations of high-dimensional data that best reveal the underlying structure. In this work, we present an intuitive and easy-to-implement method based on ranked neighborhood compariso...
IEEE/ACM transactions on computational biology and bioinformatics
Jan 1, 2015
We introduce RLIMS-P version 2.0, an enhanced rule-based information extraction (IE) system for mining kinase, substrate, and phosphorylation site information from scientific literature. Consisting of natural language processing and IE modules, the s...
International journal of data mining and bioinformatics
Jan 1, 2015
Named Entity Recognition and Classification (NERC) is an important task in information extraction for biomedicine domain. Biomedical Named Entities include mentions of proteins, genes, DNA, RNA, etc. which, in general, have complex structures and are...
Studies in health technology and informatics
Jan 1, 2015
Data quality was placed as a major reason for the low utility of patient safety event reporting systems. A pressing need in improving data quality has advanced recent research focus in data entry associated with human factors. The debate on structure...
Studies in health technology and informatics
Jan 1, 2015
Open access (OA) resources and local libraries often have their own literature databases, especially in the field of biomedicine. We have developed a method of linking a local library to a biomedical OA resource facilitating researchers' full-text ar...
Studies in health technology and informatics
Jan 1, 2015
A clinical decision support system is able to provide oncologists with suitable treatment options at the moment of decision making regarding which chemotherapy protocol is the best to apply to a particular oncological case. The National Cancer Instit...
Studies in health technology and informatics
Jan 1, 2015
This article describes the process of building an ontology to assist medical students and professionals specialized in Oncology. The ontology allows the user to obtain knowledge more quickly and thus assist professionals in their decision-making.
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