AIMC Topic:
Databases, Factual

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SAEROF: an ensemble approach for large-scale drug-disease association prediction by incorporating rotation forest and sparse autoencoder deep neural network.

Scientific reports
Drug-disease association is an important piece of information which participates in all stages of drug repositioning. Although the number of drug-disease associations identified by high-throughput technologies is increasing, the experimental methods ...

EO-MTRNN: evolutionary optimization of hyperparameters for a neuro-inspired computational model of spatiotemporal learning.

Biological cybernetics
For spatiotemporal learning with neural networks, hyperparameters are often set manually by a human expert. This is especially the case with multiple timescale networks that require a careful setting of the values of timescales in order to learn spat...

Identifying Lung Cancer Risk Factors in the Elderly Using Deep Neural Networks: Quantitative Analysis of Web-Based Survey Data.

Journal of medical Internet research
BACKGROUND: Lung cancer is one of the most dangerous malignant tumors, with the fastest-growing morbidity and mortality, especially in the elderly. With a rapid growth of the elderly population in recent years, lung cancer prevention and control are ...

Learning supervised embeddings for large scale sequence comparisons.

PloS one
Similarity-based search of sequence collections is a core task in bioinformatics, one dominated for most of the genomic era by exact and heuristic alignment-based algorithms. However, even efficient heuristics such as BLAST may not scale to the data ...

A machine learning approach on multiscale texture analysis for breast microcalcification diagnosis.

BMC bioinformatics
BACKGROUND: Screening programs use mammography as primary diagnostic tool for detecting breast cancer at an early stage. The diagnosis of some lesions, such as microcalcifications, is still difficult today for radiologists. In this paper, we proposed...

DePicT Melanoma Deep-CLASS: a deep convolutional neural networks approach to classify skin lesion images.

BMC bioinformatics
BACKGROUND: Melanoma results in the vast majority of skin cancer deaths during the last decades, even though this disease accounts for only one percent of all skin cancers' instances. The survival rates of melanoma from early to terminal stages is mo...

CAPTCHA Image Generation: Two-Step Style-Transfer Learning in Deep Neural Networks.

Sensors (Basel, Switzerland)
Mobile devices such as sensors are used to connect to the Internet and provide services to users. Web services are vulnerable to automated attacks, which can restrict mobile devices from accessing websites. To prevent such automated attacks, CAPTCHAs...

Addressing database variability in learning from medical data: An ensemble-based approach using convolutional neural networks and a case of study applied to automatic sleep scoring.

Computers in biology and medicine
In this work we examine some of the problems associated with the development of machine learning models with the objective to achieve robust generalization capabilities on common-task multiple-database scenarios. Referred to as the "database variabil...

Breaking Down Structural Diversity for Comprehensive Prediction of Ion-Neutral Collision Cross Sections.

Analytical chemistry
Identification of unknowns is a bottleneck for large-scale untargeted analyses like metabolomics or drug metabolite identification. Ion mobility-mass spectrometry (IM-MS) provides rapid two-dimensional separation of ions based on their mobility throu...