Drug-disease association is an important piece of information which participates in all stages of drug repositioning. Although the number of drug-disease associations identified by high-throughput technologies is increasing, the experimental methods ...
For spatiotemporal learning with neural networks, hyperparameters are often set manually by a human expert. This is especially the case with multiple timescale networks that require a careful setting of the values of timescales in order to learn spat...
BACKGROUND: Lung cancer is one of the most dangerous malignant tumors, with the fastest-growing morbidity and mortality, especially in the elderly. With a rapid growth of the elderly population in recent years, lung cancer prevention and control are ...
Similarity-based search of sequence collections is a core task in bioinformatics, one dominated for most of the genomic era by exact and heuristic alignment-based algorithms. However, even efficient heuristics such as BLAST may not scale to the data ...
BACKGROUND: Screening programs use mammography as primary diagnostic tool for detecting breast cancer at an early stage. The diagnosis of some lesions, such as microcalcifications, is still difficult today for radiologists. In this paper, we proposed...
BACKGROUND: Melanoma results in the vast majority of skin cancer deaths during the last decades, even though this disease accounts for only one percent of all skin cancers' instances. The survival rates of melanoma from early to terminal stages is mo...
Mobile devices such as sensors are used to connect to the Internet and provide services to users. Web services are vulnerable to automated attacks, which can restrict mobile devices from accessing websites. To prevent such automated attacks, CAPTCHAs...
In this work we examine some of the problems associated with the development of machine learning models with the objective to achieve robust generalization capabilities on common-task multiple-database scenarios. Referred to as the "database variabil...
Identification of unknowns is a bottleneck for large-scale untargeted analyses like metabolomics or drug metabolite identification. Ion mobility-mass spectrometry (IM-MS) provides rapid two-dimensional separation of ions based on their mobility throu...
BACKGROUND: Estimation of the risk of malignancy in pulmonary nodules detected by CT is central in clinical management. The use of artificial intelligence (AI) offers an opportunity to improve risk prediction. Here we compare the performance of an AI...
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