AIMC Topic: Deep Brain Stimulation
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Implications of asymmetric neural activity patterns in the basal ganglia outflow in the integrative neural network model for cervical dystonia.
Progress in brain research
Apr 30, 2019
Cervical dystonia (CD) is characterized by abnormal twisting and turning of the head with associated head oscillations. It is the most common form of dystonia, which is a third most common movement disorder. Despite frequent occurrence there is pauci...
A machine-learning approach to volitional control of a closed-loop deep brain stimulation system.
Journal of neural engineering
Nov 16, 2018
OBJECTIVE: Deep brain stimulation (DBS) is a well-established treatment for essential tremor, but may not be an optimal therapy, as it is always on, regardless of symptoms. A closed-loop (CL) DBS, which uses a biosignal to determine when stimulation ...
Automatic localization of the subthalamic nucleus on patient-specific clinical MRI by incorporating 7 T MRI and machine learning: Application in deep brain stimulation.
Human brain mapping
Oct 31, 2018
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has shown clinical potential for relieving the motor symptoms of advanced Parkinson's disease. While accurate localization of the STN is critical for consistent across-patients effective D...
A review on microelectrode recording selection of features for machine learning in deep brain stimulation surgery for Parkinson's disease.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Sep 25, 2018
OBJECTIVE: This study seeks to systematically review the selection of features and algorithms for machine learning and automation in deep brain stimulation surgery (DBS) for Parkinson's disease. This will assist in consolidating current knowledge and...
Characterization of the stimulus waveforms generated by implantable pulse generators for deep brain stimulation.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Jan 31, 2018
OBJECTIVE: To determine the circuit elements required to theoretically describe the stimulus waveforms generated by an implantable pulse generator (IPG) during clinical deep brain stimulation (DBS).
Nonlinear predictive control for adaptive adjustments of deep brain stimulation parameters in basal ganglia-thalamic network.
Neural networks : the official journal of the International Neural Network Society
Dec 7, 2017
The efficacy of deep brain stimulation (DBS) for Parkinson's disease (PD) depends in part on the post-operative programming of stimulation parameters. Closed-loop stimulation is one method to realize the frequent adjustment of stimulation parameters....
Decoding of Human Movements Based on Deep Brain Local Field Potentials Using Ensemble Neural Networks.
Computational intelligence and neuroscience
Oct 19, 2017
Decoding neural activities related to voluntary and involuntary movements is fundamental to understanding human brain motor circuits and neuromotor disorders and can lead to the development of neuromotor prosthetic devices for neurorehabilitation. Th...
A hierarchical structure for human behavior classification using STN local field potentials.
Journal of neuroscience methods
Oct 7, 2017
BACKGROUND: Classification of human behavior from brain signals has potential application in developing closed-loop deep brain stimulation (DBS) systems. This paper presents a human behavior classification using local field potential (LFP) signals re...
Intensity-based 2D 3D registration for lead localization in robot guided deep brain stimulation.
Physics in medicine and biology
Feb 7, 2017
Intraoperative assessment of lead localization has become a standard procedure during deep brain stimulation surgery in many centers, allowing immediate verification of targeting accuracy and, if necessary, adjustment of the trajectory. The most suit...
Stop! border ahead: Automatic detection of subthalamic exit during deep brain stimulation surgery.
Movement disorders : official journal of the Movement Disorder Society
Oct 6, 2016
BACKGROUND: Microelectrode recordings along preplanned trajectories are often used for accurate definition of the subthalamic nucleus (STN) borders during deep brain stimulation (DBS) surgery for Parkinson's disease. Usually, the demarcation of the S...
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