White matter fiber clustering is an important strategy for white matter parcellation, which enables quantitative analysis of brain connections in health and disease. In combination with expert neuroanatomical labeling, data-driven white matter fiber ...
Glioma is heterogeneous disease that requires classification into subtypes with similar clinical phenotypes, prognosis or treatment responses. Metabolic-protein interaction (MPI) can provide meaningful insights into cancer heterogeneity. Moreover, th...
Statistical methods in medical research
Apr 3, 2023
The uncertainty in predictions from deep neural network analysis of medical imaging is challenging to assess but potentially important to include in subsequent decision-making. Using data from diabetic retinopathy detection, we present an empirical e...
This is a retrospective analysis. Quantitative prediction of the children's and adolescents' spherical equivalent based on their variable-length historical vision records. From October 2019 to March 2022, we examined uncorrected visual acuity, sphere...
. Bloch simulation constitutes an essential part of magnetic resonance imaging (MRI) development. However, even with the graphics processing unit (GPU) acceleration, the heavy computational load remains a major challenge, especially in large-scale, h...
Quantitative phase retrieval (QPR) in propagation-based x-ray phase contrast imaging of heterogeneous and structurally complicated objects is challenging under laboratory conditions due to partial spatial coherence and polychromaticity. A deep learni...
Computational analysis of bio-images by deep learning (DL) algorithms has made exceptional progress in recent years and has become much more accessible to non-specialists with the development of ready-to-use tools. The study of oogenesis mechanisms a...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 3, 2023
A growing number of studies show that the human microbiome plays a vital role in human health and can be a crucial factor in predicting certain human diseases. However, microbiome data are often characterized by the limited samples and high-dimension...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 3, 2023
N6-methyladenosine (m6A) is a common post-transcriptional alteration that plays a critical function in a variety of biological processes. Although experimental approaches for identifying m6A sites have been developed and deployed, they are currently ...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 3, 2023
Protein secondary structure, solvent accessibility and torsion angle predictions are preliminary steps to predict 3D structure of a protein. Deep learning approaches have achieved significant improvements in predicting various features of protein str...
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