AIMC Topic: Deep Learning

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DeepDom: Predicting protein domain boundary from sequence alone using stacked bidirectional LSTM.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Protein domain boundary prediction is usually an early step to understand protein function and structure. Most of the current computational domain boundary prediction methods suffer from low accuracy and limitation in handling multi-domain types, or ...

Removing Confounding Factors Associated Weights in Deep Neural Networks Improves the Prediction Accuracy for Healthcare Applications.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
The proliferation of healthcare data has brought the opportunities of applying data-driven approaches, such as machine learning methods, to assist diagnosis. Recently, many deep learning methods have been shown with impressive successes in predicting...

The Effectiveness of Multitask Learning for Phenotyping with Electronic Health Records Data.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Electronic phenotyping is the task of ascertaining whether an individual has a medical condition of interest by analyzing their medical record and is foundational in clinical informatics. Increasingly, electronic phenotyping is performed via supervis...

Learning Contextual Hierarchical Structure of Medical Concepts with Poincairé Embeddings to Clarify Phenotypes.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Biomedical association studies are increasingly done using clinical concepts, and in particular diagnostic codes from clinical data repositories as phenotypes. Clinical concepts can be represented in a meaningful, vector space using word embedding mo...

Proteomics Analysis of FLT3-ITD Mutation in Acute Myeloid Leukemia Using Deep Learning Neural Network.

Annals of clinical and laboratory science
Deep Learning can significantly benefit cancer proteomics and genomics. In this study, we attempted to determine a set of critical proteins that were associated with the FLT3-ITD mutation in newly-diagnosed acute myeloid leukemia patients. A Deep Lea...

Artificial Intelligence and Black-Box Medical Decisions: Accuracy versus Explainability.

The Hastings Center report
Although decision-making algorithms are not new to medicine, the availability of vast stores of medical data, gains in computing power, and breakthroughs in machine learning are accelerating the pace of their development, expanding the range of quest...

[Potential applications of deep learning-based technologies in Hungarian mammography].

Orvosi hetilap
INTRODUCTION AND AIM: The technology, named 'deep learning' is the promising result of the last two decades of development in computer science. It poses an unavoidable challenge for medicine, how to understand, apply and adopt the - today not fully e...

Adverse Drug Events Detection in Clinical Notes by Jointly Modeling Entities and Relations Using Neural Networks.

Drug safety
BACKGROUND AND SIGNIFICANCE: Adverse drug events (ADEs) occur in approximately 2-5% of hospitalized patients, often resulting in poor outcomes or even death. Extraction of ADEs from clinical narratives can accelerate and automate pharmacovigilance. U...