International journal of molecular sciences
Apr 5, 2025
This study explores the role of intrinsically disordered regions (IDRs) in the SARS-CoV-2 proteome and their potential as targets for small-molecule drug discovery. Experimentally validated intrinsic disordered regions from the literature were utiliz...
BACKGROUND: Chromosomes of species exhibit a variety of high-dimensional organizational features, and chromatin loops, which are fundamental structures in the three-dimensional (3D) structure of the genome. Chromatin loops are visible speckled patter...
Identifying DNA-binding proteins and their binding residues is critical for understanding diverse biological processes, but conventional experimental approaches are slow and costly. Existing machine learning methods, while faster, often lack accuracy...
Mating behaviors are crucial for bird welfare, reproduction, and productivity in breeding flocks. During mating, a rooster mounts a hen, which may result in the hen overlapping or disappearing from top-view of a vision system. The objective of this r...
Accurate medical image segmentation is crucial for enabling automated clinical decision procedures. However, existing supervised deep learning methods for medical image segmentation face significant challenges due to their reliance on extensive label...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Apr 4, 2025
Optical coherence tomography (OCT) is a widely used imaging technology in ophthalmic clinical practice, providing non-invasive access to high-resolution retinal images. Segmentation of anatomical structures and pathological lesions in retinal OCT ima...
Conventional clinical microbiological techniques are enhanced by the introduction of artificial intelligence (AI). Comprehensive data processing and analysis enabled the development of curated datasets that has been effectively used in training diffe...
BACKGROUND: Previous knowledge-based planning studies have demonstrated the feasibility of predicting three-dimensional photon dose distributions and subsequently generating treatment plans. The steepness of dose fall-off represents a critical metric...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Apr 4, 2025
PURPOSE: To investigate the feasibility of deep-learning-based synthetic 4DCT (4D-sCT) generation from 4DMRI data of abdominal patients undergoing Carbon Ion Radiotherapy (CIRT).
The natural habitats of wild horseshoe crabs (such as beaches, shallow water areas, and intertidal sediments) are complex, posing challenges for image capture, which is often affected by real noise factors. Deep learning models are widely used in ima...
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