Cerebral cortex (New York, N.Y. : 1991)
Feb 5, 2025
Major depressive disorder (MDD) is a psychiatric disorder characterized by persistent lethargy that can lead to suicide in severe cases. Hence, timely and accurate diagnosis and treatment are crucial. Previous neuroscience studies have demonstrated t...
Depression presents a significant challenge to global mental health, often intertwined with factors including oxidative stress. Although the precise relationship with mitochondrial pathways remains elusive, recent advances in machine learning present...
Placebo effect represents a serious confounder for the assessment of treatment effect to the extent that it has become increasingly difficult to develop antidepressant medications appropriate for outperforming placebo. Treatment effect in randomized,...
Accurately predicting individual antidepressant treatment response could expedite the lengthy trial-and-error process of finding an effective treatment for major depressive disorder (MDD). We tested and compared machine learning-based methods that pr...
Major depressive disorder (MDD) is a severe psychiatric disorder that currently lacks any objective diagnostic markers. Here, we develop a deep learning approach to discover the mass spectrometric features that can discriminate MDD patients from heal...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Suicide poses a global health crisis with significant social and economic impact. Prevention may be possible if objective quantitative methods are developed to supplement the often inaccurate interview-based risk assessments. Our research goal is to ...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
While deep learning methods are increasingly applied in research contexts for neuropsychiatric disorder diagnosis, small dataset size limits their potential for clinical translation. Data augmentation (DA) could address this limitation, but the utili...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
EEG-based detection of major depression disorder (MDD) plays a pivotal role in the subsequent treatment and recovery. With the rapid development of deep learning, CNN, LSTM, and attention-based models have been used for auxiliary diagnosis of MDD fro...
MAIN PROBLEM: Anhedonia is a critical diagnostic symptom of major depressive disorder (MDD), being associated with poor prognosis. Understanding the neural mechanisms underlying anhedonia is of great significance for individuals with MDD, and it enco...
IEEE journal of biomedical and health informatics
Jul 1, 2024
Major depressive disorder (MDD) is a chronic mental illness which affects people's well-being and is often detected at a later stage of depression with a likelihood of suicidal ideation. Early detection of MDD is thus necessary to reduce the impact, ...
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