Archives of gynecology and obstetrics
Jan 20, 2026
INTRODUCTION: We aimed to develop a machine learning model for first-trimester prediction of gestational diabetes mellitus (GDM) in twin pregnancies using a prospective international, multi-center cohort and identify useful predictive markers. METHOD...
Mammalian genome : official journal of the International Mammalian Genome Society
Jan 16, 2026
Gestational diabetes mellitus (GDM) is characterized by glucose intolerance during pregnancy, resulting from insulin resistance, and is associated with increased maternal and neonatal risks. Inflammasomes play a critical role in GDM pathophysiology b...
Diabetes is a chronic condition that affects a substantial portion of the global population and is linked to elevated mortality rates and a range of severe health complications. Despite its clinical importance, progress in diabetes research is often ...
BACKGROUND AND AIM: Gestational diabetes mellitus (GDM), a common pregnancy-related metabolic disorder, often goes undiagnosed until the second trimester, limiting early intervention opportunities. Given the higher prevalence of GDM in India, there i...
Aldehyde compounds are significantly associated with diabetes mellitus. The metabolic profile of aldehydes can enhance understanding of the mechanisms underlying development of diabetes. This study employed a pair of stable isotope labeling (SIL) rea...
This study aimed to identify core genes of Gestational diabetes mellitus (GDM) and explore its immune microenvironment. Using the limma package, we were able to identify differentially expressed genes (DEGs) between GDM and normal placental tissue. W...
BACKGROUND: Gestational diabetes mellitus (GDM) affects over 5% of pregnancies worldwide, elevating risks of type 2 diabetes post partum and complications such as fetal death, miscarriage, and congenital abnormalities. Effective GDM management is ess...
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Jun 2, 2025
OBJECTIVE: To evaluate the predictive potential of first-trimester biomarkers-pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin (β-hCG)-combined with maternal body mass index (BMI), using machine learning (ML) alg...
Gestational Diabetes Mellitus (GDM) refers to any degree of impaired glucose tolerance with onset or first recognition during pregnancy. As a high-prevalence disease, GDM damages the health of both pregnant women and fetuses in the short and long ter...
BMC medical informatics and decision making
Mar 13, 2025
BACKGROUND: Gestational Diabetes Mellitus (GDM) is one of the most common medical complications during pregnancy. In the Gulf region, the prevalence of GDM is higher than in other parts of the world. Thus, there is a need for the early detection of G...
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