Dendrimer-based nanocarriers are emerging as transformative platforms to overcome the challenge of crossing the blood-brain barrier (BBB) in the treatment and diagnosis of central nervous system (CNS) disorders. Their highly branched, monodisperse ar...
International journal of pharmaceutics
Oct 15, 2025
The ophthalmic route for drug administration remains a significant constraint in ophthalmology due to the unique anatomy and several protective barriers in the eyes, which limit absorption and therapeutic efficacy. Conventionally, drugs are delivered...
Ferrohydrodynamics of blood containing magnetic nanocarriers was carried out in this study to evaluate the influence of magnetic field on the nanocarrier drug delivery formulation, with the goal of improving spatial control and efficiency in advanced...
Journal of materials science. Materials in medicine
Oct 14, 2025
Treating neurodegenerative and traumatic brain disorders is profoundly challenging due to factors like permanent tissue loss and the restrictive nature of the Blood-Brain Barrier (BBB), which limits drug delivery to the brain. Biomaterials offer a pr...
Neutrophils are the most abundant type of white blood cells in the immune system and play a complex and intricate regulatory role in disease progression. Their critical contribution to maintaining homeostasis through migration, activation, and progra...
Pancreatic cancer is one of the most lethal malignancies, largely due to the formidable pathophysiological barriers presented by its tumor microenvironment (TME). These include metabolic stress, such as acidosis and elevated reactive oxygen species; ...
Colorectal cancer (CRC) remains a major global health burden, necessitating more effective and selective therapeutic approaches. Nanocarrier-based drug delivery systems offer significant advantages by enhancing drug accumulation in tumors, reducing o...
Cancer remains one of the most significant global health challenges, with its burden continuing to rise. The limitations of conventional anticancer therapies caused by the lack of tissue selectivity, demands urgent development of safer and more selec...
Journal of agricultural and food chemistry
Oct 1, 2025
Traditional pesticide formulations suffer from poor adhesion and limited deposition efficiency, causing overuse and ecological risks. Functional nanocarriers present a promising solution by leveraging bioinspired adhesive and structural topographies ...
Neurological disorders continue to be a leading global health challenge, with the blood-brain barrier (BBB) presenting considerable obstacles to effective drug delivery for central nervous system (CNS) therapies. Accurately predicting BBB permeabilit...
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