AIMC Topic: Drug Delivery Systems

Clear Filters Showing 81 to 90 of 247 articles

A comprehensive assessment of machine learning algorithms for enhanced characterization and prediction in orodispersible film development.

International journal of pharmaceutics May 3, 2024
Orodispersible films (ODFs) have emerged as innovative pharmaceutical dosage forms, offering patient-specific treatment through adjustable dosing and the combination of diverse active ingredients. This expanding field generates vast datasets, requiri...
Drug Development Support Vector Machine Drug Delivery Systems Pilot Projects Chemistry, Pharmaceutical Dosage Forms Pharmaceutical Preparations Administration, Oral Machine Learning Algorithms
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Drug-Online: an online platform for drug-target interaction, affinity, and binding sites identification using deep learning.

BMC bioinformatics Apr 20, 2024
BACKGROUND: Accurately identifying drug-target interaction (DTI), affinity (DTA), and binding sites (DTS) is crucial for drug screening, repositioning, and design, as well as for understanding the functions of target. Although there are a few online ...
Deep Learning Drug Interactions Drug Delivery Systems Drug Evaluation, Preclinical Binding Sites
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The drug loading capacity prediction and cytotoxicity analysis of metal-organic frameworks using stacking algorithms of machine learning.

International journal of pharmaceutics Apr 15, 2024
Metal-organic frameworks (MOFs) have shown excellent performance in the field of drug delivery. Despite the synthesis of a vast array of MOFs exceeding 100,000 varieties, certain formulations have exhibited suboptimal performance characteristics. The...
Humans Machine Learning Drug Carriers Metal-Organic Frameworks Drug Delivery Systems Algorithms Cell Survival
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Advancements in microneedle fabrication techniques: artificial intelligence assisted 3D-printing technology.

Drug delivery and translational research Jan 13, 2024
Microneedles (MNs) are micron-scale needles that are a painless alternative to injections for delivering drugs through the skin. MNs find applications as biosensing devices and could serve as real-time diagnosis tools. There have been numerous fabric...
Animals Printing, Three-Dimensional Needles Microinjections Artificial Intelligence Drug Delivery Systems Humans
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Designing drugs optimized for both blood-brain barrier permeation and intra-cerebral partition.

Expert opinion on drug discovery Dec 25, 2023
INTRODUCTION: With the increasing incidence and prevalence of neurological disorders globally, there is a paramount need for new pharmacotherapies. BBB effectively protects the brain but raises a profound challenge to drug permeation, with less than ...
Drug Delivery Systems Animals Biological Transport Brain Artificial Intelligence Blood-Brain Barrier
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Ultrasound robotics for precision therapy.

Advanced drug delivery reviews Dec 23, 2023
In recent years, the application of microrobots in precision therapy has gained significant attention. The small size and maneuverability of these micromachines enable them to potentially access regions that are difficult to reach using traditional m...
Drug Delivery Systems Humans Robotics
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Use of Artificial Intelligence to Improve the Calculation of Percent Adhesion for Transdermal and Topical Delivery Systems.

Journal of medical systems Dec 18, 2023
Adhesion is a critical quality attribute and performance characteristic for transdermal and topical delivery systems (TDS). Regulatory agencies recommend in vivo skin adhesion studies to support the approval of TDS in both new drug applications and a...
Humans Administration, Cutaneous Drug Delivery Systems Artificial Intelligence Technology Skin
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A deep learning method for drug-target affinity prediction based on sequence interaction information mining.

PeerJ Dec 11, 2023
BACKGROUND: A critical aspect of drug discovery involves the prediction of drug-target affinity (DTA). Conducting wet lab experiments to determine affinity is both expensive and time-consuming, making it necessary to find alternative approaches. In ...
Biological Evolution Drug Delivery Systems Drug Discovery Deep Learning
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Delivering drugs with microrobots.

Science (New York, N.Y.) Dec 7, 2023
Biomedical microrobots could overcome current challenges in targeted therapies.
Humans Drug Delivery Systems Robotics
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Towards multifunctional robotic pills.

Nature biomedical engineering Sep 18, 2023
Robotic pills leverage the advantages of oral pharmaceutical formulations-in particular, convenient encapsulation, high loading capacity, ease of manufacturing and high patient compliance-as well as the multifunctionality, increasing miniaturization ...
Equipment Design Administration, Oral Robotics Microinjections Humans Drug Delivery Systems Animals
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