AIMC Topic: Drug Development

Clear Filters Showing 321 to 330 of 333 articles

Deep Learning in Drug Target Interaction Prediction: Current and Future Perspectives.

Current medicinal chemistry
Drug-target Interactions (DTIs) prediction plays a central role in drug discovery. Computational methods in DTIs prediction have gained more attention because carrying out in vitro and in vivo experiments on a large scale is costly and time-consuming...

Application of machine intelligence technology in the detection of vaccines and medicines for SARS-CoV-2.

European review for medical and pharmacological sciences
Researchers have found many similarities between the 2003 severe acute respiratory syndrome (SARS) virus and SARS-CoV-19 through existing data that reveal the SARS's cause. Artificial intelligence (AI) learning models can be created to predict drug s...

Artificial intelligence: a disruptive tool for a smarter medicine.

European review for medical and pharmacological sciences
OBJECTIVE: Although highly successful, the medical R&D model is failing at improving people's health due to a series of flaws and defects inherent to the model itself. A new collective intelligence, incorporating human and artificial intelligence (AI...

Exploring the Potential of Artificial Intelligence and Machine Learning to Combat COVID-19 and Existing Opportunities for LMIC: A Scoping Review.

Journal of primary care & community health
BACKGROUND: In the face of the current time-sensitive COVID-19 pandemic, the limited capacity of healthcare systems resulted in an emerging need to develop newer methods to control the spread of the pandemic. Artificial Intelligence (AI), and Machine...

Drug knowledge bases and their applications in biomedical informatics research.

Briefings in bioinformatics
Recent advances in biomedical research have generated a large volume of drug-related data. To effectively handle this flood of data, many initiatives have been taken to help researchers make good use of them. As the results of these initiatives, many...

Current status and future perspective of computational toxicology in drug safety assessment under ontological intellection.

The Journal of toxicological sciences
For the safety assessment of pharmaceuticals, initial data management requires accurate toxicological data acquisition, which is based on regulatory safety studies according to guidelines, and computational systems have been developed under the appli...