Metals in stormwater can be toxic to organisms, particularly when occurring in truly dissolved form (fraction <3 kDa). Here, using 153 samples collected during six rains, we investigated intra-events variations of total, dissolved and truly dissolved...
Environmental pollution (Barking, Essex : 1987)
Feb 17, 2022
Poor air quality is becoming a critical environmental concern in different countries over the last several years. Most of the air pollutants have serious consequences on human health and wellbeing. In this context, efficient forecasting of air pollut...
It is an important topic in environmental sciences to understand the behavior and toxicology of chemical pollutants. Quantum chemical methodologies have served as useful tools for probing behavior and toxicology of chemical pollutants in recent decad...
Microplastic pollution of stormwater can be a serious threat to the environment. Gross pollutant trap (GPT) - bioretention treatment trains have been shown previously to treat (inter alia) particulate stormwater pollutants including microplastic part...
Biological assays are useful in water quality evaluation by providing the overall toxicity of chemical mixtures in environmental waters. However, it is impossible to elucidate the source of toxicity and some lethal combination of pollutants simply us...
The mechanisms leading to organ level toxicities are poorly understood. In this study, we applied an integrated approach to deduce the molecular targets and biological pathways involved in chemically induced toxicity for eight common human organ leve...
Environmental pollution (Barking, Essex : 1987)
Dec 4, 2019
Cypermethrin is a frequently used insecticide in agriculture and households but its chronic and molecular effects are poorly known are . Here we describe effects of sublethal cypermethrin exposure on the global transcriptome in the brain of honey bee...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Mar 1, 2019
Humans and wildlife inhabit a world with panoply of natural and synthetic chemicals. Alarmingly, only a limited number of chemicals have undergone comprehensive toxicological evaluation due to limitations of traditional toxicity testing. High-through...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Jan 10, 2019
In silico toxicity prediction plays an important role in the regulatory decision making and selection of leads in drug design as in vitro/vivo methods are often limited by ethics, time, budget, and other resources. Many computational methods have bee...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Jan 10, 2019
We introduce here ML4Tox, a framework offering Deep Learning and Support Vector Machine models to predict agonist, antagonist, and binding activities of chemical compounds, in this case for the estrogen receptor ligand-binding domain. The ML4Tox mode...