We present prediction and variable importance (VIM) methods for longitudinal data sets containing continuous and binary exposures subject to missingness. We demonstrate the use of these methods for prognosis of medical outcomes of severe trauma patie...
BACKGROUND: Robotic technology commenced to be adopted for the field of general surgery in the 1990s. Since then, the da Vinci surgical system (Intuitive Surgical Inc, Sunnyvale, CA, USA) has remained by far the most commonly used system in this doma...
Journal of the American Medical Informatics Association : JAMIA
Feb 5, 2015
OBJECTIVE: For many literature review tasks, including systematic review (SR) and other aspects of evidence-based medicine, it is important to know whether an article describes a randomized controlled trial (RCT). Current manual annotation is not com...
Studies in health technology and informatics
Aug 7, 2025
The fundamental process of evidence extraction in evidence-based medicine relies on identifying PICO elements, with Outcomes being the most complex and often overlooked. To address this, we introduce EvidenceOutcomes, a large annotated corpus of clin...
Lung cancer is the leading cause of cancer-related mortality worldwide. Early lung cancer detection improves lung cancer-related mortality and survival. This report summarizes presentations and panel discussions from a webinar, "The Present and Futur...
Studies in health technology and informatics
May 15, 2025
Large Language Models (LLMs) offer potential for automating systematic reviews, a labor-intensive process in evidence-based medicine. We evaluated GPT-4o, GPT-4o-mini, and Llama 3.1:8B on abstract screening and risk of bias assessment using 12 Cochra...
Journal of the Medical Library Association : JMLA
Jan 14, 2025
OBJECTIVE: This study investigated the performance of a generative artificial intelligence (AI) tool using GPT-4 in answering clinical questions in comparison with medical librarians' gold-standard evidence syntheses.
Studies in health technology and informatics
Aug 22, 2024
Systematic review and meta-analysis constitute a staple of evidence-based medicine, an obligatory step in developing the guideline and recommendation document. It is a formalized process aiming at extracting and summarizing knowledge from the publish...
Investigative ophthalmology & visual science
Aug 1, 2024
Artificial intelligence (AI) health technologies are increasingly available for use in real-world care. This emerging opportunity is accompanied by a need for decision makers and practitioners across healthcare systems to evaluate the safety and effe...
BACKGROUND: Alzheimer's disease (AD), a major dementia cause, lacks effective treatment. MRI-based hippocampal volume measurement using artificial intelligence offers new insights into early diagnosis and intervention in AD progression.
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