Docosahexaenoic acid (DHA), an essential ω-3 polyunsaturated fatty acid, is efficiently biosynthesized by Schizochytrium sp., yet its bioprocess optimization remains constrained by dynamic interdependencies between cultivation parameters and metaboli...
This review explores the health benefits of bioactive peptides (BAPs) from fermented milk proteins, emphasizing the transformative role of artificial intelligence (AI) and machine learning (ML) in advancing this field. BAPs exhibit diverse biological...
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
40170318
As a strategic emerging industry, biomanufacturing faces core challenges in achieving precise optimization and efficient scale-up of fermentation processes. This review focuses on two critical aspects of fermentation-real-time sensing and intelligent...
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
40170304
Biomanufacturing is an advanced manufacturing method that integrates biology, chemistry, and engineering. It utilizes renewable biomass and biological organisms as production media to scale up the production of target products through fermentation. C...
International journal of biological macromolecules
40139616
The application of machine learning in pullulan biofermentation has demonstrated significant potential. Explainable machine learning enhances model transparency and interpretability by revealing the relationships between variables. In this study, we ...
The lignocellulosic biorefinery involves pretreatment, enzymatic hydrolysis, mixed sugar fermentation, and optional anaerobic digestion. This pipeline could be effectively implemented through machine learning (ML)-guided process optimization and stra...
International journal of biological macromolecules
40101811
This study focuses on optimizing the fermentation process for the production of low molecular weight welan gum (LMW-WG) using Sphingomonas sp. ATCC 31555 with glycerol as the sole carbon source. A series of single-factor experiments were conducted to...
Nicotinamide mononucleotide (NMN) is a bioactive compound in NAD(P) metabolism, which exhibits diverse pharmaceutical interests. However, enhancing NMN biosynthesis faces the challange of competing with cell growth and disturbing intracellular redox ...
Pixian Douban (PXDB) meju is a crucial intermediate product in the PXDB production. In this study, a machine vision system was employed to monitor and evaluate the meju quality quickly to replace the time-consuming chemical methods. The results of co...
Coffee pulp wine was made from coffee pulp. The level range of fermentation factors was determined by one-factor experiment. The significance factors affecting fermentation were screened by Plackett-Burman and steepest climbing experiments, which wer...