AIMC Topic: Gemcitabine

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Monitoring vascular normalization induced by antiangiogenic treatment with (18)F-fluoromisonidazole-PET.

Molecular oncology Dec 22, 2015
BACKGROUND: Rationalization of antiangiogenics requires biomarkers. Vascular re-normalization is one widely accepted mechanism of action for this drug class. The interstitium of tumors with abnormal vasculature is hypoxic. We sought to track vascular...
Humans Female Breast Neoplasms Animals Cell Line, Tumor Mice Angiogenesis Inhibitors Mice, Nude Pancreatic Neoplasms Breast Positron-Emission Tomography Quinolones Neovascularization, Pathologic Pancreas Cell Hypoxia Fluorine Radioisotopes Benzimidazoles Antimetabolites, Antineoplastic Deoxycytidine Gemcitabine Misonidazole
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Genomic signatures for paclitaxel and gemcitabine resistance in breast cancer derived by machine learning.

Molecular oncology Aug 22, 2015
Increasingly, the effectiveness of adjuvant chemotherapy agents for breast cancer has been related to changes in the genomic profile of tumors. We investigated correspondence between growth inhibitory concentrations of paclitaxel and gemcitabine (GI5...
Humans Machine Learning Female Breast Neoplasms Antineoplastic Agents Cell Line, Tumor Support Vector Machine Paclitaxel Drug Resistance, Neoplasm Deoxycytidine Gemcitabine
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[Radical Resection of cT3a Gallbladder Cancer after Neoadjuvant Chemotherapy - A Case Report].

Gan to kagaku ryoho. Cancer & chemotherapy Nov 1, 2016
We report a case of a radical resection of cT3a gallbladder cancer after neoadjuvant chemotherapy(NAC). A 68-year-old man was referred to our hospital with a chief complaint of right hypochondralgia.Imaging findings were consistent with acute cholecy...
Humans Aged Male Antineoplastic Combined Chemotherapy Protocols Neoadjuvant Therapy Lymphatic Metastasis Neoplasm Staging Cisplatin Deoxycytidine Gemcitabine Cholecystitis, Acute Gallbladder Neoplasms
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