AIMC Topic: Genome
Clear Filters Showing 161 to 170 of 175 articles
DeepGSR: an optimized deep-learning structure for the recognition of genomic signals and regions.
Bioinformatics (Oxford, England)
Apr 1, 2019
MOTIVATION: Recognition of different genomic signals and regions (GSRs) in DNA is crucial for understanding genome organization, gene regulation, and gene function, which in turn generate better genome and gene annotations. Although many methods have...
ME-Class2 reveals context dependent regulatory roles for 5-hydroxymethylcytosine.
Nucleic acids research
Mar 18, 2019
Since the discovery of 5-hydroxymethylcytosine (5hmC) as a prominent DNA modification found in mammalian genomes, an emergent question has been what role this mark plays in gene regulation. 5hmC is hypothesized to function as an intermediate in the d...
The Splicing Code Goes Deep.
Cell
Jan 24, 2019
The importance of genomic sequence context in generating transcriptome diversity through RNA splicing is independently unmasked by two studies in this issue (Jaganathan et al., 2019; Baeza-Centurion et al., 2019).
ARIADNA: machine learning method for ancient DNA variant discovery.
DNA research : an international journal for rapid publication of reports on genes and genomes
Dec 1, 2018
Ancient DNA (aDNA) studies often rely on standard methods of mutation calling, optimized for high-quality contemporary DNA but not for excessive contamination, time- or environment-related damage of aDNA. In the absence of validated datasets and desp...
A graph-embedded deep feedforward network for disease outcome classification and feature selection using gene expression data.
Bioinformatics (Oxford, England)
Nov 1, 2018
MOTIVATION: Gene expression data represents a unique challenge in predictive model building, because of the small number of samples (n) compared with the huge amount of features (p). This 'n≪p' property has hampered application of deep learning techn...
LeNup: learning nucleosome positioning from DNA sequences with improved convolutional neural networks.
Bioinformatics (Oxford, England)
May 15, 2018
MOTIVATION: Nucleosome positioning plays significant roles in proper genome packing and its accessibility to execute transcription regulation. Despite a multitude of nucleosome positioning resources available on line including experimental datasets o...
Neopepsee: accurate genome-level prediction of neoantigens by harnessing sequence and amino acid immunogenicity information.
Annals of oncology : official journal of the European Society for Medical Oncology
Apr 1, 2018
BACKGROUND: Tumor-specific mutations form novel immunogenic peptides called neoantigens. Neoantigens can be used as a biomarker predicting patient response to cancer immunotherapy. Although a predicted binding affinity (IC50) between peptide and majo...
Genome-wide pre-miRNA discovery from few labeled examples.
Bioinformatics (Oxford, England)
Feb 15, 2018
MOTIVATION: Although many machine learning techniques have been proposed for distinguishing miRNA hairpins from other stem-loop sequences, most of the current methods use supervised learning, which requires a very good set of positive and negative ex...
Unhidden Figures.
Cell systems
Dec 27, 2017
Complementary Sources of Protein Functional Information: The Far Side of GO.
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2017
The GO captures many aspects of functional annotations, but there are other alternative complementary sources of protein function information. For example, enzyme functional annotations are described in a range of resources from the Enzyme Commission...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31037
- Neural Networks, Computer 29719
- Algorithms 26832
- Deep Learning 26346
- Artificial Intelligence 24295
- Robotics 13311
- Image Processing, Computer-Assisted 9521
- Retrospective Studies 9111
- Magnetic Resonance Imaging 6181
- Reproducibility of Results 5592
- Tomography, X-Ray Computed 4771
- Support Vector Machine 4686
- Computational Biology 4237
- Brain 4050
- Computer Simulation 3881
Recent Journals
- Scientific reports 5949
- Sensors (Basel, Switzerland) 4794
- PloS one 4015
- Neural networks : the official journal of the International Neural Network Society 2930
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1859
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1130
- Journal of chemical information and modeling 998
- Nature communications 944
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 861
- Briefings in bioinformatics 853
- IEEE transactions on neural networks and learning systems 826