International journal of computer assisted radiology and surgery
Sep 17, 2014
PURPOSEĀ : Tumor grading plays an essential role in the optimal selection of solid tumor treatment. Noninvasive methods are needed for clinical grading of tumors. This study aimed to extract parameters of resting state blood oxygenation level-dependen...
Gliomas exhibit significant heterogeneity and diverse molecular subtypes, and there are marked differences in treatment strategies and prognoses for gliomas of different grades and molecular types. However, current glioma molecular subtyping systems ...
Deep learning (DL) has shown promise in glioma imaging tasks using magnetic resonance imaging (MRI) and histopathology images, yet their complexity demands greater transparency in artificial intelligence (AI) systems. This is noticeable when users mu...
BACKGROUND: Determining whether pediatric patients with low-grade gliomas (pLGGs) have tumor-related epilepsy (GAE) is a crucial aspect of preoperative evaluation. Therefore, we aim to propose an innovative, machine learning- and deep learning-based ...
BACKGROUND: The newest glioma classification in WHO 2021 emphasizes the importance of gene mutations in the glioma molecular pathogenesis. Our research aims to look for new glioma-related genes that have the potential to be therapeutic targets.
UNLABELLED: Diagnostic delays in patients with brain cancer are common and can impact patient outcome. Development of a blood-based assay for detection of brain cancers could accelerate brain cancer diagnosis. In this study, we analyzed genome-wide c...
OBJECTIVES: Accurate and noninvasive detection of p53 status in isocitrate dehydrogenase mutant (IDH-mt) glioma is clinically meaningful for molecular stratification of glioma, yet it remains challenging. We aimed to investigate the diagnostic effica...
Neuropathology : official journal of the Japanese Society of Neuropathology
Aug 1, 2025
This study aimed to evaluate the performance of ChatGPT-4.0 as a diagnostic support tool for pathologists in identifying different types of gliomas based on histopathological data and to compare its performance with that of another artificial intelli...
Neuropathology and applied neurobiology
Aug 1, 2025
Gliomas, with their intricate and aggressive nature, call for a detailed visualisation of their vasculature. Traditional 2D imaging often overlooks the spatial heterogeneity of tumours. Our study overcomes this by combining tissue clearing, 3D-confoc...
Diffuse midline glioma (DMG) is a rare, aggressive, and fatal tumor that largely occurs in the pediatric population. To improve outcomes, it is important to characterize DMGs, which can be performed via magnetic resonance imaging (MRI) assessment. Re...
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