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Growth Disorders

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Quality of Life in Adolescent Boys with Idiopathic Short Stature: Positive Impact of Growth Hormone and Aromatase Inhibitors.

Hormone research in paediatrics
BACKGROUND: The combination of growth hormone (GH) and aromatase inhibitors (AI) improves linear growth in severely short adolescent boys; however, the effects of this intervention on quality of life (QoL) are unknown. This study assesses whether GH,...

Machine learning-based prediction of response to growth hormone treatment in Turner syndrome: the LG Growth Study.

Journal of pediatric endocrinology & metabolism : JPEM
Background Growth hormone (GH) treatment has become a common practice in Turner syndrome (TS). However, there are only a few studies on the response to GH treatment in TS. The aim of this study is to predict the responsiveness to GH treatment and to ...

Machine learning model demonstrates stunting at birth and systemic inflammatory biomarkers as predictors of subsequent infant growth - a four-year prospective study.

BMC pediatrics
BACKGROUND: Stunting affects up to one-third of the children in low-to-middle income countries (LMICs) and has been correlated with decline in cognitive capacity and vaccine immunogenicity. Early identification of infants at risk is critical for earl...

Sociodemographic risk factors of under-five stunting in Bangladesh: Assessing the role of interactions using a machine learning method.

PloS one
This paper aims to demonstrate the importance of studying interactions among various sociodemographic risk factors of childhood stunting in Bangladesh with the help of an interpretable machine learning method. Data used for the analyses are extracted...

Model and variable selection using machine learning methods with applications to childhood stunting in Bangladesh.

Informatics for health & social care
Childhood stunting is a serious public health concern in Bangladesh. Earlier research used conventional statistical methods to identify the risk factors of stunting, and very little is known about the applications and usefulness of machine learning (...

Digital technologies to improve the precision of paediatric growth disorder diagnosis and management.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Paediatric disorders of impaired linear growth are challenging to manage, in part because of delays in the identification of pathological short stature and subsequent referral and diagnosis, the requirement for long-term therapy, and frequent poor ad...