AIMC Topic: Humans

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MTRRE-Net: A deep learning model for detection of breast cancer from histopathological images.

Computers in biology and medicine
Histopathological image classification has become one of the most challenging tasks among researchers due to the fine-grained variability of the disease. However, the rapid development of deep learning-based models such as the Convolutional Neural Ne...

A deep learning model for detection of Alzheimer's disease based on retinal photographs: a retrospective, multicentre case-control study.

The Lancet. Digital health
BACKGROUND: There is no simple model to screen for Alzheimer's disease, partly because the diagnosis of Alzheimer's disease itself is complex-typically involving expensive and sometimes invasive tests not commonly available outside highly specialised...

DeepClassPathway: Molecular pathway aware classification using explainable deep learning.

European journal of cancer (Oxford, England : 1990)
OBJECTIVE: HPV-associated head and neck cancer is correlated with favorable prognosis; however, its underlying biology is not fully understood. We propose an explainable convolutional neural network (CNN) classifier, DeepClassPathway, that predicts H...

Development of a deep learning-based quantitative structure-activity relationship model to identify potential inhibitors against the 3C-like protease of SARS-CoV-2.

Future medicinal chemistry
In the recent COVID-19 pandemic, SARS-CoV-2 infection spread worldwide. TheĀ 3C-like protease (3CLpro) is a promising drug target for SARS-CoV-2. We constructed a deep learning-based convolutional neural network-quantitative structure-activity relat...

Automatic Liver Tumor Segmentation on Dynamic Contrast Enhanced MRI Using 4D Information: Deep Learning Model Based on 3D Convolution and Convolutional LSTM.

IEEE transactions on medical imaging
OBJECTIVE: Accurate segmentation of liver tumors, which could help physicians make appropriate treatment decisions and assess the effectiveness of surgical treatment, is crucial for the clinical diagnosis of liver cancer. In this study, we propose a ...

Fully-Automated Spike Detection and Dipole Analysis of Epileptic MEG Using Deep Learning.

IEEE transactions on medical imaging
Magnetoencephalography (MEG) is a useful tool for clinically evaluating the localization of interictal spikes. Neurophysiologists visually identify spikes from the MEG waveforms and estimate the equivalent current dipoles (ECD). However, presently, t...

Echocardiography Segmentation With Enforced Temporal Consistency.

IEEE transactions on medical imaging
Convolutional neural networks (CNN) have demonstrated their ability to segment 2D cardiac ultrasound images. However, despite recent successes according to which the intra-observer variability on end-diastole and end-systole images has been reached, ...

MOOD 2020: A Public Benchmark for Out-of-Distribution Detection and Localization on Medical Images.

IEEE transactions on medical imaging
Detecting Out-of-Distribution (OoD) data is one of the greatest challenges in safe and robust deployment of machine learning algorithms in medicine. When the algorithms encounter cases that deviate from the distribution of the training data, they oft...

Integrative Histology-Genomic Analysis Predicts Hepatocellular Carcinoma Prognosis Using Deep Learning.

Genes
Cancer prognosis analysis is of essential interest in clinical practice. In order to explore the prognostic power of computational histopathology and genomics, this paper constructs a multi-modality prognostic model for survival prediction. We collec...