Humans

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A rank weighted classification for plasma proteomic profiles based on case-based reasoning.

BMC medical informatics and decision making May 31, 2018
BACKGROUND: It is a challenge to precisely classify plasma proteomic profiles into their clinical status based solely on their patterns even though distinct patterns of plasma proteomic profiles are regarded as potential to be a biomarker because the...
Blood Proteomics Proteome Medical Informatics Artificial Intelligence Biomarkers Humans
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A Composite Model of Wound Segmentation Based on Traditional Methods and Deep Neural Networks.

Computational intelligence and neuroscience May 31, 2018
Wound segmentation plays an important supporting role in the wound observation and wound healing. Current methods of image segmentation include those based on traditional process of image and those based on deep neural networks. The traditional metho...
Image Interpretation, Computer-Assisted Machine Learning Humans Wounds and Injuries Wound Healing Neural Networks, Computer Skin
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Soft tissue deformation modelling through neural dynamics-based reaction-diffusion mechanics.

Medical & biological engineering & computing May 30, 2018
Soft tissue deformation modelling forms the basis of development of surgical simulation, surgical planning and robotic-assisted minimally invasive surgery. This paper presents a new methodology for modelling of soft tissue deformation based on reacti...
Anisotropy Computer Simulation Connective Tissue Feedback Biomechanical Phenomena Diffusion Phantoms, Imaging Models, Anatomic Humans Neural Networks, Computer
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Prediction of Human Cytochrome P450 Inhibition Using a Multitask Deep Autoencoder Neural Network.

Molecular pharmaceutics May 30, 2018
Adverse side effects of drug-drug interactions induced by human cytochrome P450 (CYP450) inhibition is an important consideration in drug discovery. It is highly desirable to develop computational models that can predict the inhibitive effect of a co...
Humans Neural Networks, Computer Machine Learning Quantitative Structure-Activity Relationship Protein Isoforms Cytochrome P-450 Enzyme Inhibitors Algorithms Drug Interactions Cytochrome P-450 Enzyme System
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Pattern analysis of computer keystroke time series in healthy control and early-stage Parkinson's disease subjects using fuzzy recurrence and scalable recurrence network features.

Journal of neuroscience methods May 30, 2018
BACKGROUND: Identifying patients with early stages of Parkinson's disease (PD) in a home environment is an important area of neurological disorder research, because it is of therapeutic and economic benefits to optimal intervention and management of ...
Cohort Studies Fuzzy Logic Parkinson Disease Predictive Value of Tests Nonlinear Dynamics Recurrence Machine Learning Female Male Humans Gait Disorders, Neurologic Neural Networks, Computer
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TernaryNet: faster deep model inference without GPUs for medical 3D segmentation using sparse and binary convolutions.

International journal of computer assisted radiology and surgery May 30, 2018
PURPOSE: Deep convolutional neural networks (DCNN) are currently ubiquitous in medical imaging. While their versatility and high-quality results for common image analysis tasks including segmentation, localisation and prediction is astonishing, the l...
Support Vector Machine Pancreas Humans Neural Networks, Computer Algorithms Tomography, X-Ray Computed Imaging, Three-Dimensional
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Deep learning in ophthalmology: a review.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie May 30, 2018
Deep learning is an emerging technology with numerous potential applications in Ophthalmology. Deep learning tools have been applied to different diagnostic modalities including digital photographs, optical coherence tomography, and visual fields. Th...
Eye Diseases Humans Diagnostic Techniques, Ophthalmological Diagnosis, Computer-Assisted Deep Learning Ophthalmology
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Structural brain changes versus self-report: machine-learning classification of chronic fatigue syndrome patients.

Experimental brain research May 30, 2018
Chronic fatigue syndrome (CFS) is a disorder associated with fatigue, pain, and structural/functional abnormalities seen during magnetic resonance brain imaging (MRI). Therefore, we evaluated the performance of structural MRI (sMRI) abnormalities in ...
Humans Machine Learning Fatigue Syndrome, Chronic Male Middle Aged Image Processing, Computer-Assisted Brain Female Adult Self Report Magnetic Resonance Imaging Models, Neurological
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Heart disease diagnosis based on mediative fuzzy logic.

Artificial intelligence in medicine May 30, 2018
Mediative fuzzy logic is an approach able to deal with inconsistent information providing a solution when contradiction exists. The aim of this paper is to design an expert system based on this type of fuzzy logic in order to diagnose a possible hear...
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Humans Reproducibility of Results Risk Factors Heart Diseases Diagnosis, Computer-Assisted Expert Systems Fuzzy Logic Uncertainty Predictive Value of Tests
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A portable structural analysis library for reaction networks.

Bio Systems May 30, 2018
The topology of a reaction network can have a significant influence on the network's dynamical properties. Such influences can include constraints on network flows and concentration changes or more insidiously result in the emergence of feedback loop...
Computer Simulation Systems Biology Programming Languages Structure-Activity Relationship Cell Physiological Phenomena Humans Neural Networks, Computer Software Algorithms
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