AIMC Topic: Integrin alphaVbeta3

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The Interplay Between Epithelial-Mesenchymal Transition (EMT) and the Thyroid Hormones-αvβ3 Axis in Ovarian Cancer.

Hormones & cancer Dec 19, 2017
Ovarian cancer is a highly metastatic disease. The metastatic potential is enhanced by epithelial to mesenchymal transition (EMT) in which αvβ3 integrin plays a role. Thyroid hormones (L-thyroxine, T4, and 3,5,3'-triiodo-L-thyronine, T3) bind this in...
Humans Female Cell Line, Tumor Gene Expression Regulation, Neoplastic Signal Transduction Ovarian Neoplasms Zonula Occludens-1 Protein Epithelial-Mesenchymal Transition Thyroxine Cadherins Thyroid Hormones Vimentin Triiodothyronine beta Catenin Integrin alphaVbeta3 Snail Family Transcription Factors Zinc Finger E-box-Binding Homeobox 1
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Preparation of arginine-glycine-aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization.

International journal of nanomedicine Dec 30, 2016
Neovascularization (NV) of the cornea can disrupt visual function, causing ocular diseases, including blindness. Therefore, treatment of corneal NV has a high public health impact. Epigalloccatechin-3-gallate (EGCG), presenting antiangiogenesis effec...
Humans Animals Nanoparticles Angiogenesis Inhibitors Disease Models, Animal Mice, Inbred C57BL Cell Survival Burns, Chemical Human Umbilical Vein Endothelial Cells Ophthalmic Solutions Hyaluronic Acid Catechin Molecular Targeted Therapy Oligopeptides Integrin alphaVbeta3 Corneal Neovascularization Eye Burns
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