AIMC Topic: Intention to Treat Analysis

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Using the counterfactual framework to estimate non-intention-to-treat estimands in randomised controlled trials: A methodological scoping review.

Contemporary clinical trials Apr 11, 2025
BACKGROUND: Randomised controlled trials (RCTs) commonly estimate intention-to-treat (ITT) estimands. However, when nonadherence to assigned treatment occurs, ITT estimands reflect the effect of being offered treatment, rather than adhering to it and...
Humans Research Design Intention to Treat Analysis Scoping Review as Topic Data Interpretation, Statistical Randomized Controlled Trials as Topic
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Use of a Novel Artificial Intelligence System Leads to the Detection of Significantly Higher Number of Adenomas During Screening and Surveillance Colonoscopy: Results From a Large, Prospective, US Multicenter, Randomized Clinical Trial.

The American journal of gastroenterology Jan 18, 2024
INTRODUCTION: Adenoma per colonoscopy (APC) has recently been proposed as a quality measure for colonoscopy. We evaluated the impact of a novel artificial intelligence (AI) system, compared with standard high-definition colonoscopy, for APC measureme...
Artificial Intelligence Prospective Studies Humans Colorectal Neoplasms Male Aged Female Intention to Treat Analysis Adenoma Colonic Polyps Early Detection of Cancer Colonoscopy Predictive Value of Tests United States Middle Aged
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Dynamic impact of transfusion ratios on outcomes in severely injured patients: Targeted machine learning analysis of the Pragmatic, Randomized Optimal Platelet and Plasma Ratios randomized clinical trial.

The journal of trauma and acute care surgery Sep 1, 2020
BACKGROUND: Massive transfusion protocols to treat postinjury hemorrhage are based on predefined blood product transfusion ratios followed by goal-directed transfusion based on patient's clinical evolution. However, it remains unclear how these trans...
North America Intention to Treat Analysis Trauma Centers Wounds and Injuries Humans Hemostasis Blood Component Transfusion Erythrocytes Female Male Machine Learning Hemorrhage Plasma Blood Platelets
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Defining the Role of Minimally Invasive Proctectomy for Locally Advanced Rectal Adenocarcinoma.

Annals of surgery Oct 1, 2017
OBJECTIVE: National examination of open proctectomy (OP), laparoscopic proctectomy (LP), and robotic proctectomy (RP) in pathological outcomes and overall survival (OS).
Male Adenocarcinoma Retrospective Studies Treatment Outcome Robotics Chemotherapy, Adjuvant Middle Aged Rectum Female Neoadjuvant Therapy Humans Kaplan-Meier Estimate Rectal Neoplasms Laparoscopy Neoplasm Staging Intention to Treat Analysis Chemoradiotherapy, Adjuvant Proportional Hazards Models Digestive System Surgical Procedures
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