Patients with cirrhosis used to be associated with frequent use of blood components because of their complex disorder of hemostasis and bleeding complications. Recent findings have indicated that patients with cirrhosis have a state of "rebalanced" o...
Improving the treatment of trauma, a leading cause of death worldwide, is of great clinical and public health interest. This analysis introduces flexible statistical methods for estimating center-level effects on individual outcomes in the context of...
Statistical techniques such as propensity score matching and instrumental variable are commonly employed to "simulate" randomization and adjust for measured confounders in comparative effectiveness research. Despite such adjustments, the results of t...
The journal of trauma and acute care surgery
32520897
BACKGROUND: Massive transfusion protocols to treat postinjury hemorrhage are based on predefined blood product transfusion ratios followed by goal-directed transfusion based on patient's clinical evolution. However, it remains unclear how these trans...