The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe improvements and expansions to...
OBJECTIVES: The secondary use of clinical data provides large opportunities for clinical and translational research as well as quality assurance projects. For such purposes, it is necessary to provide a flexible and scalable infrastructure that is co...
The Gene Ontology Annotation (GOA) resource (http://www.ebi.ac.uk/GOA) provides evidence-based Gene Ontology (GO) annotations to proteins in the UniProt Knowledgebase (UniProtKB). Manual annotations provided by UniProt curators are supplemented by ma...
Adverse drug reactions (ADRs) are noxious and unexpected effects during normal drug therapy. They have caused significant clinical burden and been responsible for a large portion of new drug development failure. Molecular understanding and in silico ...
Biologists often pose queries to search engines and biological databases to obtain answers related to ongoing experiments. This is known to be a time consuming, and sometimes frustrating, task in which more than one query is posed and many databases ...
The current version of the Human Disease Ontology (DO) (http://www.disease-ontology.org) database expands the utility of the ontology for the examination and comparison of genetic variation, phenotype, protein, drug and epitope data through the lens ...
Journal of diabetes science and technology
Jan 1, 2011
BACKGROUND: As America's baby boom generation reaches retirement, the number of elders, and, in turn, the number of lay individuals who support them, will continue to increase. With the important services caregivers provide, it is critical that we re...
BACKGROUND: Artificial intelligence-driven technologies offer transformative potential in plastic surgery, spanning preoperative planning, surgical procedures, and postoperative care, with the promise of improved patient outcomes.
It is clear that artificial intelligence-based chatbots will be popular applications in the field of healthcare in the near future. It is known that more than 30% of the world's population suffers from chronic pain and individuals try to access the h...
The organization of subcellular components in a cell is critical for its function and studying cellular processes, protein-protein interactions, identifying potential drug targets, network analysis, and other systems biology mechanisms. Determining p...