AIMC Topic: Knowledge Bases

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ICG: a wiki-driven knowledgebase of internal control genes for RT-qPCR normalization.

Nucleic acids research
Real-time quantitative PCR (RT-qPCR) has become a widely used method for accurate expression profiling of targeted mRNA and ncRNA. Selection of appropriate internal control genes for RT-qPCR normalization is an elementary prerequisite for reliable ex...

miRandola 2017: a curated knowledge base of non-invasive biomarkers.

Nucleic acids research
miRandola (http://mirandola.iit.cnr.it/) is a database of extracellular non-coding RNAs (ncRNAs) that was initially published in 2012, foreseeing the relevance of ncRNAs as non-invasive biomarkers. An increasing amount of experimental evidence shows ...

Clinical Data Warehouse Query and Learning Tool Using a Human-Centered Participatory Design Process.

Studies in health technology and informatics
BMI Investigator (BMII) is an interactive web-based tool with a learning knowledge base, which provides a way for researchers to query structured, unstructured, genomic and image data contained in a data warehouse. We demonstrate how development of a...

Radiation Oncology Terminology Linker: A Step Towards a Linked Data Knowledge Base.

Studies in health technology and informatics
Performing image feature extraction in radiation oncology is often dependent on the organ and tumor delineations provided by clinical staff. These delineation names are free text DICOM metadata fields resulting in undefined information, which require...

Personalized Knowledge Transfer for Caregiving Relatives.

Studies in health technology and informatics
Caregiving relatives have to manage very diverse tasks and need a lot of care-relevant knowledge. For most of them it is not easy to find the knowledge required. Thus, a personalized knowledge transfer for caregiving relatives is necessary. Against t...

An Automated Technique to Construct a Knowledge Base of Traditional Chinese Herbal Medicine for Cancers: An Exploratory Study for Breast Cancer.

Studies in health technology and informatics
Traditional Chinese Medicine utilization has rapidly increased worldwide. However, there is limited database provides the information of TCM herbs and diseases. The study aims to identify and evaluate the meaningful associations between TCM herbs and...

Combining the Generic Entity-Attribute-Value Model and Terminological Models into a Common Ontology to Enable Data Integration and Decision Support.

Studies in health technology and informatics
The integration of clinical information models and termino-ontological models into a unique ontological framework is highly desirable for it facilitates data integration and management using the same formal mechanisms for both data concepts and infor...

A Knowledge-Base for a Personalized Infectious Disease Risk Prediction System.

Studies in health technology and informatics
We present a knowledge-base to represent collated infectious disease risk (IDR) knowledge. The knowledge is about personal and contextual risk of contracting an infectious disease obtained from declarative sources (e.g. Atlas of Human Infectious Dise...

Health Care Leadership: Managing Knowledge Bases as Stakeholders.

The health care manager
Communities are composed of many organizations. These organizations naturally form clusters based on common patterns of knowledge, skills, and abilities of the individual organizations. Each of these spontaneous clusters represents a distinct knowled...