AIMC Topic: Knowledge Bases

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KNOWLEDGE-ASSISTED APPROACH TO IDENTIFY PATHWAYS WITH DIFFERENTIAL DEPENDENCIES.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
We have previously developed a statistical method to identify gene sets enriched with condition-specific genetic dependencies. The method constructs gene dependency networks from bootstrapped samples in one condition and computes the divergence betwe...

[Development of a Knowledge-based Application Utilizing Ontologies for the Continuing Site-specific JJ1017 Master Maintenance].

Nihon Hoshasen Gijutsu Gakkai zasshi
The purpose of this study was to develop the JJ1017 Knowledge-based Application (JKA) to support the continuing maintenance of a site-specific JJ1017 master defined by the JJ1017 guideline as a standard radiologic procedure master for medical informa...

DAPD: A Knowledgebase for Diabetes Associated Proteins.

IEEE/ACM transactions on computational biology and bioinformatics
Recent advancements in genomics and proteomics provide a solid foundation for understanding the pathogenesis of diabetes. Proteomics of diabetes associated pathways help to identify the most potent target for the management of diabetes. The relevant ...

Practice innovation: the need for nimble data platforms to implement precision oncology care.

Discovery medicine
Given the drive toward personalized, value-based, and coordinated cancer care delivery, modern knowledge-based practice is being shaped within the context of an increasingly technology-driven healthcare landscape. The ultimate promise of 'precision m...

Ontology-based Semantic Support to Improve Accessibility of Graphics.

Studies in health technology and informatics
We aim to ease the process of authoring accessible graphics as well as taking a first step towards the long-term goal of allowing blind persons to access graphics autonomously. We are developing and experimenting with a hierarchical set of knowledge ...