MOTIVATION: The rapid growth in literature accumulates diverse and yet comprehensive biomedical knowledge hidden to be mined such as drug interactions. However, it is difficult to extract the heterogeneous knowledge to retrieve or even discover the l...
Studies in health technology and informatics
Jan 14, 2022
Patients, relatives, doctors, and healthcare providers anticipate the evidence-based length of stay (LOS) prediction in neurosurgery. This study aimed to assess the quality of LOS prediction with the GPT3 language model upon the narrative medical rec...
Studies in health technology and informatics
Jan 14, 2022
Processing unstructured clinical texts is often necessary to support certain tasks in biomedicine, such as matching patients to clinical trials. Among other methods, domain-specific language models have been built to utilize free-text information. Th...
MOTIVATION: As one of the most important post-translational modifications (PTMs), protein lysine crotonylation (Kcr) has attracted wide attention, which involves in important physiological activities, such as cell differentiation and metabolism. Howe...
Mathematical biosciences and engineering : MBE
Jan 4, 2022
Named entities are the main carriers of relevant medical knowledge in Electronic Medical Records (EMR). Clinical electronic medical records lead to problems such as word segmentation ambiguity and polysemy due to the specificity of Chinese language s...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2022
In biomedicine, facts about relations between entities (disease, gene, drug, etc.) are hidden in the large trove of 30 million scientific publications. The curated information is proven to play an important role in various applications such as drug r...
BACKGROUND: Mild cognitive impairment (MCI), which is common in older adults, is a risk factor for dementia. Rapidly growing health care demand associated with global population aging has spurred the development of new digital tools for the assessmen...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2022
Artificial intelligence (AI) offers new possibilities for hit and lead finding in medicinal chemistry. Several instances of AI have been used for prospective de novo drug design. Among these, chemical language models have been shown to perform well i...
Studies in health technology and informatics
Nov 18, 2021
The important information about a patient is often stored in a free-form text to describe the events in the patient's medical history. In this work, we propose and evaluate a hybrid approach based on rules and syntactical analysis to normalise tempor...
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