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Lymphatic Metastasis

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Preoperative prediction of regional lymph node metastasis of colorectal cancer based on F-FDG PET/CT and machine learning.

Annals of nuclear medicine
PURPOSE: To establish and validate a regional lymph node (LN) metastasis prediction model of colorectal cancer (CRC) based on F-FDG PET/CT and radiomic features using machine-learning methods.

Predicting gastric cancer outcome from resected lymph node histopathology images using deep learning.

Nature communications
N-staging is a determining factor for prognostic assessment and decision-making for stage-based cancer therapeutic strategies. Visual inspection of whole-slides of intact lymph nodes is currently the main method used by pathologists to calculate the ...

Machine learning-based prediction model using clinico-pathologic factors for papillary thyroid carcinoma recurrence.

Scientific reports
This study analyzed the prognostic significance of clinico-pathologic factors, including the number of metastatic lymph nodes (LNs) and lymph node ratio (LNR), in patients with papillary thyroid carcinoma (PTC), and attempted to construct a disease r...

Data-efficient and weakly supervised computational pathology on whole-slide images.

Nature biomedical engineering
Deep-learning methods for computational pathology require either manual annotation of gigapixel whole-slide images (WSIs) or large datasets of WSIs with slide-level labels and typically suffer from poor domain adaptation and interpretability. Here we...

Attention Guided Lymph Node Malignancy Prediction in Head and Neck Cancer.

International journal of radiation oncology, biology, physics
PURPOSE: Accurate lymph node (LN) malignancy classification is essential for treatment target identification in head and neck cancer (HNC) radiation therapy. Given the constraints imposed by relatively small sample sizes in real-world medical applica...

Artificial intelligence for the diagnosis of lymph node metastases in patients with abdominopelvic malignancy: A systematic review and meta-analysis.

Artificial intelligence in medicine
PURPOSE: Accurate clinical diagnosis of lymph node metastases is of paramount importance in the treatment of patients with abdominopelvic malignancy. This review assesses the diagnostic performance of deep learning algorithms and radiomics models for...

Deep learning system for lymph node quantification and metastatic cancer identification from whole-slide pathology images.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
BACKGROUND: Traditional diagnosis methods for lymph node metastases are labor-intensive and time-consuming. As a result, diagnostic systems based on deep learning (DL) algorithms have become a hot topic. However, current research lacks testing with s...

A machine learning-based radiomics model for the prediction of axillary lymph-node metastasis in breast cancer.

Breast cancer (Tokyo, Japan)
OBJECTIVE: The aim of this study was to develop and validate machine learning-based radiomics model for predicting axillary lymph-node (ALN) metastasis in invasive ductal breast cancer (IDC) using F-18 fluorodeoxyglucose (FDG) positron emission tomog...

Machine learning predicts lymph node metastasis of poorly differentiated-type intramucosal gastric cancer.

Scientific reports
To construct a machine learning algorithm model of lymph node metastasis (LNM) in patients with poorly differentiated-type intramucosal gastric cancer. 1169 patients with postoperative gastric cancer were divided into a training group and a test grou...

LASSO-Based Machine Learning Algorithm for Prediction of Lymph Node Metastasis in T1 Colorectal Cancer.

Cancer research and treatment
PURPOSE: The role of tumor-infiltrating lymphocytes (TILs) in predicting lymph node metastasis (LNM) in patients with T1 colorectal cancer (CRC) remains unclear. Furthermore, clinical utility of a machine learning-based approach has not been widely s...