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Lymphopenia

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A novel deep learning model using dosimetric and clinical information for grade 4 radiotherapy-induced lymphopenia prediction.

Physics in medicine and biology
Radiotherapy-induced lymphopenia has increasingly been shown to reduce cancer survivorship. We developed a novel hybrid deep learning model to efficiently integrate an entire set of dosimetric parameters of a radiation treatment plan with a patient's...

Personalized Composite Dosimetric Score-Based Machine Learning Model of Severe Radiation-Induced Lymphopenia Among Patients With Esophageal Cancer.

International journal of radiation oncology, biology, physics
PURPOSE: Radiation-induced lymphopenia (RIL) is common among patients undergoing radiation therapy (RT)' Severe RIL has been linked to adverse outcomes. The severity and risk of RIL can be predicted from baseline clinical characteristics and dosimetr...

Interpretable deep learning insights: Unveiling the role of 1 Gy volume on lymphopenia after radiotherapy in breast cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND: Lymphopenia is known for its significance on poor survivals in breast cancer patients. Considering full dosimetric data, this study aimed to develop and validate predictive models for lymphopenia after radiotherapy (RT) in breast cancer.