AIMC Topic: Machine Learning

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Decoding IBD progression: a dynamic biomarker atlas for personalized disease stratification.

Journal of translational medicine
BACKGROUND: Accurate staging is pivotal for tailoring treatment intensity, optimizing resource allocation, and improving long-term patient outcomes in IBD. The intestinal microbiota and transcriptional profiles emerge as critical determinants in IBD ...

DNA methylation and machine learning: challenges and perspective toward enhanced clinical diagnostics.

Clinical epigenetics
DNA methylation is an epigenetic modification that regulates gene expression by adding methyl groups to DNA, affecting cellular function and disease development. Machine learning, a subset of artificial intelligence, analyzes large datasets to identi...

Machine learning-based integration of pericoronary adipose tissue and clinical risk factors for cardiovascular risk prediction in type 2 diabetes: a retrospective cohort study.

European journal of medical research
BACKGROUND: Cardiovascular disease remains the predominant cause of morbidity and mortality in individuals with type 2 diabetes mellitus (T2DM). Traditional risk models are limited in predictive accuracy. Pericoronary adipose tissue (PCAT), a novel i...

Investigating the role of depression in obstructive sleep apnea and predicting risk factors for OSA in depressed patients: machine learning-assisted evidence from NHANES.

BMC psychiatry
OBJECTIVE: The relationship between depression and obstructive sleep apnea (OSA) remains controversial. Therefore, this study aims to explore their association and utilize machine learning models to predict OSA among individuals with depression withi...

Semi-automatic detection of anteriorly displaced temporomandibular joint discs in magnetic resonance images using machine learning.

BMC oral health
BACKGROUND: Accurate diagnosis of anterior disc displacement (ADD) is essential for managing temporomandibular joint disorders (TMJ). This study employed machine learning (ML) to automatically detect anteriorly displaced TMJ discs in magnetic resonan...

Predicting outcomes in pediatric patients with acute kidney injury: a retrospective single-center cohort study using machine learning models.

BMC medical informatics and decision making
OBJECTIVE: To develop and evaluate machine learning models combined with survival analysis for predicting 7-, 14-, and 28-day mortality in critically ill children with acute kidney injury (AKI), identifying key predictors to guide risk stratification...

Identification and tissue-level validation of ferroptosis-related genes in small intestinal neuroendocrine neoplasms based on machine learning.

BMC gastroenterology
BACKGROUND: Small intestinal neuroendocrine neoplasms (SI-NENs), a subgroup of neuroendocrine tumors originating from neuroendocrine cells in the small intestine, present significant therapeutic challenges, and their relationship with ferroptosis-a r...

Utilization of sequential model-based optimizer integrated machine learning models in correlation of famotidine solubility in supercritical carbon dioxide.

Scientific reports
We investigated solubility variations of a medication in supercritical carbon dioxide with an insight into preparation of nanomedicines with improved aqueous solubility. As the case study, the solubility of famotidine (FAM) medicine in sc-CO (supercr...

Conventional and hybrid time series models for forecasting medication dispensing and errors integration in automated dispensing cabinets.

Scientific reports
Automated dispensing cabinets (ADCs) represent a critical innovation in modern healthcare, revolutionizing medication management by improving efficiency, accuracy, and security. With the increasing reliance on these technologies, optimizing their per...

Machine learning analysis of coagulation-related genes for breast cancer diagnosis and prognosis prediction.

Scientific reports
The purpose of this study was to investigate the relationship between coagulation related genes (CRGs) and breast cancer (BC). First, we found that most CRGs are abnormally expressed in BC patients and correlated with their prognosis. Therefore, we e...