PURPOSE: There is increasing interest in computed tomography (CT) image estimations from magnetic resonance (MR) images. The estimated CT images can be utilized for attenuation correction, patient positioning, and dose planning in diagnostic and radi...
PURPOSE: This paper proposes a sinogram-consistency learning method to deal with beam hardening-related artifacts in polychromatic computerized tomography (CT). The presence of highly attenuating materials in the scan field causes an inconsistent sin...
The farnesoid X receptor (FXR) emerges as a promising drug target involved in regulating various metabolic pathways, yet some xenobiotic compounds binding to FXR would be an important determinant to induce the receptor dysfunctions that lead to undes...
Environmental science and pollution research international
Nov 7, 2018
River water temperature is a key control of many physical and bio-chemical processes in river systems, which theoretically depends on multiple factors. Here, four different machine learning models, including multilayer perceptron neural network model...
AJR. American journal of roentgenology
Nov 7, 2018
OBJECTIVE: Machine learning has potential to play a key role across a variety of medical imaging applications. This review seeks to elucidate the ways in which machine learning can aid and enhance diagnosis, treatment, and follow-up in neurooncology.
Particulate matter with aerodynamic diameter less than 2.5 μm (PM) is a complex mixture of chemical constituents emitted from various emission sources or through secondary reactions/processes; however, PM is regulated mostly based on its total mass c...
Patients with drug-resistant epilepsy (DRE) are at high risk of morbidity and mortality, yet their referral to specialist care is frequently delayed. The ability to identify patients at high risk of DRE at the time of treatment initiation, and to sub...
Alternative splicing (AS) is generally regulated by trans-splicing factors that specifically bind to cis-elements in pre-mRNAs. The human genome encodes ∼1,500 RNA binding proteins (RBPs) that potentially regulate AS, yet their functions remain large...
Magnetic resonance imaging (MRI) has been proposed as a complimentary method to measure bone quality and assess fracture risk. However, manual segmentation of MR images of bone is time-consuming, limiting the use of MRI measurements in the clinical p...
Following Cas9 cleavage, DNA repair without a donor template is generally considered stochastic, heterogeneous and impractical beyond gene disruption. Here, we show that template-free Cas9 editing is predictable and capable of precise repair to a pre...
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