Here we present the results of residue-residue contact predictions achieved in CASP11 by the CONSIP2 server, which is based around our MetaPSICOV contact prediction method. On a set of 40 target domains with a median family size of around 40 effectiv...
Neural networks : the official journal of the International Neural Network Society
Aug 14, 2015
This paper introduces an on-line semi-supervised learning algorithm formulated as a regularized kernel spectral clustering (KSC) approach. We consider the case where new data arrive sequentially but only a small fraction of it is labeled. The availab...
MOTIVATION: Protein contact prediction is important for protein structure and functional study. Both evolutionary coupling (EC) analysis and supervised machine learning methods have been developed, making use of different information sources. However...
IEEE journal of biomedical and health informatics
Aug 13, 2015
In this paper, a novel subject-adaptable heartbeat classification model is presented, in order to address the significant interperson variations in ECG signals. A multiview learning approach is proposed to automate subject adaptation using a small am...
International journal of medical informatics
Aug 13, 2015
OBJECTIVE: Death certificates provide an invaluable source for cancer mortality statistics; however, this value can only be realised if accurate, quantitative data can be extracted from certificates--an aim hampered by both the volume and variable na...
Neural networks : the official journal of the International Neural Network Society
Aug 12, 2015
In this paper we consider the training of single hidden layer neural networks by pseudoinversion, which, in spite of its popularity, is sometimes affected by numerical instability issues. Regularization is known to be effective in such cases, so that...
OBJECTIVES: This paper aims to predict childhood obesity after age two, using only data collected prior to the second birthday by a clinical decision support system called CHICA.
Journal of the American Medical Informatics Association : JAMIA
Aug 7, 2015
OBJECTIVE: Hospitals are challenged to provide timely patient care while maintaining high resource utilization. This has prompted hospital initiatives to increase patient flow and minimize nonvalue added care time. Real-time demand capacity managemen...
What adolescents say when they think about or attempt suicide influences the medical care they receive. Mental health professionals use teenagers' words, actions, and gestures to gain insight into their emotional state and to prescribe what they beli...
Journal of the American Medical Informatics Association : JAMIA
Aug 7, 2015
OBJECTIVE: This paper presents an automatic, active learning-based system for the extraction of medical concepts from clinical free-text reports. Specifically, (1) the contribution of active learning in reducing the annotation effort and (2) the robu...
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